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Merck
CN

E1001

Sigma-Aldrich

炔孕酮

≥99% (HPLC)

别名:

17α-乙炔睾酮, 17β-羟基-4,17α-孕甾烯-20-炔基-3-酮, 4,17α-孕甾烯-17β-醇-20-炔基-3-酮

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关于此项目

经验公式（希尔记法）:
C21H28O2
CAS Number:
434-03-7
分子量:
312.45
Beilstein:
1889895
EC 号:
207-096-5
MDL编号:
MFCD00003656
UNSPSC代码:
12352200
PubChem化学物质编号:
24894377
NACRES:
NA.77

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生物来源

synthetic (organic)

质量水平

200

无菌性

non-sterile

方案

≥99% (HPLC)

表单

powder

药品控制

regulated under CDSA - not available from Sigma-Aldrich Canada

技术

cell culture | mammalian: suitable

mp

263-269 °C (lit.)

溶解性

chloroform: methanol (1:1): 20 mg/mL, clear to slightly hazy, colorless to light yellow

创始人

Novartis

运输

ambient

储存温度

room temp

SMILES字符串

C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2CC[C@@]4(C)[C@H]3CC[C@@]4(O)C#C

InChI

1S/C21H28O2/c1-4-21(23)12-9-18-16-6-5-14-13-15(22)7-10-19(14,2)17(16)8-11-20(18,21)3/h1,13,16-18,23H,5-12H2,2-3H3/t16-,17+,18+,19+,20+,21+/m1/s1

InChI key

CHNXZKVNWQUJIB-CEGNMAFCSA-N

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一般描述

Ethisterone is a progestogen. It is a danazol derivative.

应用

Ethisterone has been used as a component in Dulbecco′s modified eagle medium (DMEM) to culture the transfected COS-7 cell for transient transfection assay and gene transfection assay.

生化/生理作用

Ethisterone acts as a progestational agent. It is consumed by pregnant mothers to prevent miscarriage.

特点和优势

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

象形图

Health hazardEnvironment
GHS08,GHS09

警示用语：

Danger

危险声明

H360FD,H410

危险分类

Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 1A

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

个人防护装备

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

监管及禁止进口产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCN6152
BCCM4999
BCCJ8386
BCCF8924
BCCB5708

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Precise spatiotemporal regulation of signaling activators and inhibitors can help limit developmental crosstalk between neighboring tissues during morphogenesis, homeostasis, and regeneration. Here, we find that the secreted Wnt inhibitor Dkk1b is abundantly produced by dense regions of androgen-regulated epidermal tubercles
Cloning and expression analysis of androgen receptor gene in chicken embryogenesis
Katoh H, et al.
Febs Letters, 580(6), 1607-1615 (2006)
The inhibitory effects of danazol, danazol metabolites, gestrinone, and testosterone on the growth of human endometrial cells in vitro
Fertility and Sterility, 49(2), 224-228 (1988)
Ambiguous Genitalia in the Newborn
Avery's Diseases of the Newborn, 1286-1306 (2012)
Evolutionary History and Functional Characterization of Androgen Receptor Genes in Jawed Vertebrates
Ogino Y, et al.
Endocrinology, 150(12), 5415-5427 (2009)
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