主要文件

查看所有文档

E101

S-(−)-Eticlopride 盐酸盐

Name: S-(&#8722;)-Eticlopride 盐酸盐
Brand: SIGMA

≥98% (HPLC), D2 dopamine receptor antagonist, powder

别名:

FLB 131, S-(−)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide 盐酸盐

登录查看组织和合同定价。

选择尺寸

变更视图

关于此项目

经验公式（希尔记法）:

C₁₇H₂₅ClN₂O₃ · HCl

化学文摘社编号:

97612-24-3

分子量:

377.31

UNSPSC Code:

12352200

PubChem Substance ID:

24278428

NACRES:

NA.77

MDL number:

MFCD00055132

Assay:

≥98% (HPLC)

Form:

powder

Quality level:

100

Storage condition:

desiccated

技术服务

需要帮助？我们经验丰富的科学家团队随时乐意为您服务。

让我们为您提供帮助

产品名称

S-(−)-Eticlopride 盐酸盐, ≥98% (HPLC), powder

Quality Level

100

assay

≥98% (HPLC)

form

powder

optical activity

[α]27/D −7.2°, c = 0.3 in methanol(lit.)

storage condition

desiccated

color

off-white

solubility

H₂O: soluble >10 mg/mL, ethanol: soluble 2.6 mg/mL, 0.1 M HCl: soluble 7 mg/mL

SMILES string

Cl.CCN1CCC[C@H]1CNC(=O)c2c(O)c(CC)cc(Cl)c2OC

InChI

1S/C17H25ClN2O3.ClH/c1-4-11-9-13(18)16(23-3)14(15(11)21)17(22)19-10-12-7-6-8-20(12)5-2;/h9,12,21H,4-8,10H2,1-3H3,(H,19,22);1H/t12-;/m0./s1

InChI key

HFJFXXDHVWLIKX-YDALLXLXSA-N

Gene Information

human ... DRD2(1813)

Application

S-(-)-盐酸依替必利已用于星形胶质细胞-神经元共培养和官能性磁共振成像 (fMRI) 实验。

Biochem/physiol Actions

强效和选择性 D2 多巴胺受体拮抗剂。依替必利对 DAD2 受体的特异性高于匹莫齐特或氟哌啶醇。编码D2多巴胺受体（DRD2）的基因与包括帕金森病在内的多种疾病、精神分裂症和酒精中毒易感性有关。

Preparation Note

溶液可在 4° C下储存数天

Legal Information

经 Astra AB 许可生产和销售。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

0000354623

0000104443

0000136150

没有发现合适的版本？

如果您需要特殊版本，可通过批号或批次号查找具体证书。

搜索COA

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Bradykinin B2 receptor and dopamine D2 receptor cooperatively contribute to the regulation of neutrophil adhesion to endothelial cells.

Anna Niewiarowska-Sendo et al.

Acta biochimica Polonica, 65(3), 367-375 (2018-08-28)

Leukocyte adhesion to the vascular endothelium contributes to many immunological and inflammatory disorders. These processes have been shown to be mediated by bradykinin receptor type 2 (B2R) and dopamine receptor type 2 (D2R). In a previous study, we reported the

Regional in vivo binding of the substituted benzamide [3H]eticlopride in the rat brain: evidence for selective labelling of dopamine receptors.

C Köhler et al.

European journal of pharmacology, 120(2), 217-226 (1986-01-21)

The novel substituted benzamide eticlopride, (S)-(-)-5-chloro-3-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-methoxy salicylamide hydrochloride (A38503; FLB 131), was radiolabelled to high specific activity and used for in vivo receptor binding studies in the rat brain. Intravenous injections of [3H]eticlopride resulted in a rapid accumulation of radioactivity

Resilient yet entirely degradable gelatin-based biogels for soft robots and electronics.

Melanie Baumgartner et al.

Nature materials, 19(10), 1102-1109 (2020-06-17)

Biodegradable and biocompatible elastic materials for soft robotics, tissue engineering or stretchable electronics with good mechanical properties, tunability, modifiability or healing properties drive technological advance, and yet they are not durable under ambient conditions and do not combine all the

The dopamine D2 antagonist eticlopride accelerates extinction and delays reacquisition of food self-administration in rats

Koerber J, et al.

Behavioural Pharmacology, 24(8), 633-633 (2013)

Structure and linkage of the D2 dopamine receptor and neural cell adhesion molecule genes on human chromosome 11q23

Eubanks J H, et al.

Genomics, 14(4), 1010-1018 (1992)

查看所有相关文献

全球贸易项目编号

货号	GTIN
E101-100MG	04061832090597
E101-25MG	04061832090603
330116-50G	04061826725863

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系客户支持