Name: β-雌二醇17-(β-<SC>D</SC>-葡萄糖醛酸) 钠盐
Brand: SIGMA

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About This Item

线性分子式:

C₂₄H₃₁O₈Na

CAS Number:

15087-02-2

分子量:

470.49

MDL编号:

MFCD00056557

UNSPSC代码:

51111800

PubChem化学物质编号:

24894388

NACRES:

NA.77

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Product Name

β-雌二醇17-(β-D-葡萄糖醛酸) 钠盐,

无菌性

non-sterile

质量水平

200

方案

≥98% (HPLC)

表单

powder

溶解性

0.1 M NaOH: 10 mg/mL, clear to slightly hazy, colorless to faintly yellow

运输

ambient

储存温度

−20°C

SMILES字符串

[Na].CC12CCC3C(CCc4cc(O)ccc34)C1CCC2OC5OC(C(O)C(O)C5O)C(O)=O

InChI

1S/C24H32O8.Na.H/c1-24-9-8-14-13-5-3-12(25)10-11(13)2-4-15(14)16(24)6-7-17(24)31-23-20(28)18(26)19(27)21(32-23)22(29)30;;/h3,5,10,14-21,23,25-28H,2,4,6-9H2,1H3,(H,29,30);;

InChI key

GPLPNZUTAJWRLU-UHFFFAOYSA-N

应用

β-Estradiol 17-(β-D-glucuronide) sodium salt has been used as a standard to determine the quantity of β-Estradiol 17-(β-D-glucuronide) during UDP-glucuronosyltransferase assay. It has also been used as a constituent of modified synthetic oviduct fluid (m-SOF) for maturation of bovine cumulus oocyte complexes (COC).

生化/生理作用

Estradiol 17-(β-D-glucuronide) (E217G) is a naturally occurring conjugated estrogen. It is formed in the liver and later excreted in bile. Increased concentrations of E217G leads to the development of cholestasis during the later stages of pregnancy, a condition which occurs with high frequency in the Dubin-Johnson syndrome.

特点和优势

This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.