主要文件

查看所有文档

E1127

β-雌二醇17-(β-D-葡萄糖醛酸) 钠盐

Name: &#946;-雌二醇17-(&#946;-<SC>D</SC>-葡萄糖醛酸) 钠盐
Brand: SIGMA

≥98% (HPLC), Estradiol metabolite, powder

别名:

1,3,5(10)-Estratriene-3,17β-diol 17-glucuronide, 3,17β-Dihydroxy-1,3,5(10)-estratriene 17-glucuronide

登录查看组织和合同定价。

选择尺寸

变更视图

关于此项目

线性分子式:

C₂₄H₃₁O₈Na

化学文摘社编号:

15087-02-2

分子量:

470.49

UNSPSC Code:

51111800

PubChem Substance ID:

24894388

NACRES:

NA.77

MDL number:

MFCD00056557

Assay:

≥98% (HPLC)

Form:

powder

Quality level:

200

技术服务

需要帮助？我们经验丰富的科学家团队随时乐意为您服务。

让我们为您提供帮助

产品名称

β-雌二醇17-(β-D-葡萄糖醛酸) 钠盐,

sterility

non-sterile

Quality Level

200

assay

≥98% (HPLC)

form

powder

solubility

0.1 M NaOH: 10 mg/mL, clear to slightly hazy, colorless to faintly yellow

shipped in

ambient

storage temp.

−20°C

SMILES string

[Na].CC12CCC3C(CCc4cc(O)ccc34)C1CCC2OC5OC(C(O)C(O)C5O)C(O)=O

InChI

1S/C24H32O8.Na.H/c1-24-9-8-14-13-5-3-12(25)10-11(13)2-4-15(14)16(24)6-7-17(24)31-23-20(28)18(26)19(27)21(32-23)22(29)30;;/h3,5,10,14-21,23,25-28H,2,4,6-9H2,1H3,(H,29,30);;

InChI key

GPLPNZUTAJWRLU-UHFFFAOYSA-N

Application

β-Estradiol 17-(β-D-glucuronide) sodium salt has been used as a standard to determine the quantity of β-Estradiol 17-(β-D-glucuronide) during UDP-glucuronosyltransferase assay. It has also been used as a constituent of modified synthetic oviduct fluid (m-SOF) for maturation of bovine cumulus oocyte complexes (COC).

Biochem/physiol Actions

Estradiol 17-(β-D-glucuronide) (E217G) is a naturally occurring conjugated estrogen. It is formed in the liver and later excreted in bile. Increased concentrations of E217G leads to the development of cholestasis during the later stages of pregnancy, a condition which occurs with high frequency in the Dubin-Johnson syndrome.

Features and Benefits

This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

pictograms

GHS08,GHS07

signalword

Warning

hcodes

H302 + H312 + H332,H351

pcodes

P202 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P308 + P313

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2

存储类别

11 - Combustible Solids

wgk

WGK 3

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

涉药品监管产品

此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

0000353229

0000376255

0000285933

没有发现合适的版本？

如果您需要特殊版本，可通过批号或批次号查找具体证书。

搜索COA

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

ATP-dependent 17-Estradiol 17-(-D-Glucuronide) Transport by Multidrug Resistance Protein (MRP) INHIBITION BY CHOLESTATIC STEROIDS

Loe DW, et al.

The Journal of Biological Chemistry, 271, 9683-9689 (1996)

Vascular endothelial growth factor has beneficial effect independent of serum components throughout oocyte maturation and early embryonic development in cattle

Luo H, et al.

Asian-Australasian Journal of Animal Sciences, 19(4), 495-499 (2006)

Vascular endothelial growth factor (VEGF) promotes the early development of bovine embryo in the presence of cumulus cells