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经验公式(希尔记法):
C18H24O3
化学文摘社编号:
分子量:
288.38
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
51111800
EC Number:
200-022-2
MDL number:
Beilstein/REAXYS Number:
2508172
Assay:
≥97%
Form:
powder
产品名称
雌三醇, ≥97%
biological source
synthetic (organic)
Quality Segment
sterility
non-sterile
assay
≥97%
form
powder
mp
280-282 °C (lit.)
solubility
pyridine: 50 mg/mL, clear, colorless to faintly brownish-yellow
shipped in
ambient
storage temp.
room temp
SMILES string
C[C@]12CC[C@H]3[C@@H](CCc4cc(O)ccc34)[C@@H]1C[C@@H](O)[C@@H]2O
InChI
1S/C18H24O3/c1-18-7-6-13-12-5-3-11(19)8-10(12)2-4-14(13)15(18)9-16(20)17(18)21/h3,5,8,13-17,19-21H,2,4,6-7,9H2,1H3/t13-,14-,15+,16-,17+,18+/m1/s1
InChI key
PROQIPRRNZUXQM-ZXXIGWHRSA-N
Gene Information
human ... SERPINA6(866)
mouse ... Esr1(13982)
rat ... Ar(24208)
Application
Estriol has been used as a sex hormone to determine its binding constants to insulin (INS), the insulin receptor (IR), and INS-like peptides derived from the IR.
Biochem/physiol Actions
Estriol is a metabolite of 17β-estradiol with much lower biological activity. It is the primary estrogen found in the urine. Large quantities of estriol and estrone are produced by the placenta during pregnancy. These are also the primary estrogens produced by adipose tissue in men and post-menopausal women. Estriol may exhibit immunomodulatory benefits against various diseases such as autoimmune, inflammatory, and neurodegenerative conditions.
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Danger
hcodes
Hazard Classifications
Carc. 2 - Lact. - Repr. 1A
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
