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Merck
CN

E1260

Sigma-Aldrich

L-乙硫氨基酪酸

≥99% (TLC)

别名:

L-2-氨基-4-(乙硫基)丁酸

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关于此项目

线性分子式:
C2H5SCH2CH2CH(NH2)CO2H
CAS Number:
13073-35-3
分子量:
163.24
EC 号:
235-966-4
MDL编号:
MFCD00002626
UNSPSC代码:
12352209
PubChem化学物质编号:
24894397
NACRES:
NA.26

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Product Name

L-乙硫氨基酪酸, ≥99% (TLC)

质量水平

100

方案

≥99% (TLC)

表单

powder

颜色

white

mp

280 °C (dec.) (lit.)

储存温度

−20°C

SMILES字符串

CCSCC[C@H](N)C(O)=O

InChI

1S/C6H13NO2S/c1-2-10-4-3-5(7)6(8)9/h5H,2-4,7H2,1H3,(H,8,9)/t5-/m0/s1

InChI key

GGLZPLKKBSSKCX-YFKPBYRVSA-N

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相关类别

生化/生理作用

甲硫氨酸类似物，会干扰 DNA 的标准甲基化和其他甲基化途径，从而导致胰腺中毒和肝癌。但在动物研究中，也显示出与甲硫氨酸消耗的同步活动，以阻止甲硫氨酸依赖性肿瘤的生长和转移。

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H315,H319,H335

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
MKCX4404
MKCT7298
MKCV0062
MKCQ0606
MKCN9399

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Aymeric Goyer et al.
Plant & cell physiology, 48(2), 232-242 (2006-12-16)
Methionine gamma-lyase (MGL) catalyzes the degradation of L-methionine to alpha-ketobutyrate, methanethiol and ammonia. The Arabidopsis (Arabidopsis thaliana) genome includes a single gene (At1g64660) encoding a protein (AtMGL) with approximately 35% identity to bacterial and protozoan MGLs. When overexpressed in Escherichia
Joanne N Tonkin et al.
Stem cell research, 1(3), 195-204 (2009-04-23)
Liver progenitor (oval) cells have enormous potential in the treatment of patients with liver disease using a cell therapy approach, but their use is limited by their scarcity and the number of donor livers from which they can be derived.
Shuntaro Ikeda et al.
The Journal of reproduction and development, 58(1), 91-97 (2011-11-05)
The roles of methionine metabolism in bovine preimplantation embryo development were investigated by using ethionine, an antimetabolite of methionine. In vitro produced bovine embryos that had developed to the 5-cell stage or more at 72 h after the commencement of
Erik Alm et al.
Analytical and bioanalytical chemistry, 396(5), 1681-1689 (2010-01-21)
This work addresses the subject of time-series analysis of comprehensive (1)H-NMR data of biological origin. One of the problems with toxicological and efficacy studies is the confounding of correlation between the administered drug, its metabolites and the systemic changes in
Noémi Van Hul et al.
The American journal of pathology, 179(4), 1839-1850 (2011-08-23)
Activation of myofibroblasts (MF) and extracellular matrix (ECM) deposition predispose the expansion and differentiation of liver progenitor cells (LPC) during chronic liver injury. Because Kupffer cells (KC) are active modulators of tissue response and fibrosis, we analyzed their role in
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