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关于此项目
经验公式(希尔记法):
C11H10O3
化学文摘社编号:
分子量:
190.20
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12161501
EC Number:
250-429-4
MDL number:
Beilstein/REAXYS Number:
146200
产品名称
7-乙氧基香豆素,
assay
≥99.45% (HPLC)
Quality Level
form
powder
mp
88-90 °C (lit.)
solubility
95% ethanol: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow
fluorescence
λex 323 nm; λem 386 nm
SMILES string
CCOc1ccc2C=CC(=O)Oc2c1
InChI
1S/C11H10O3/c1-2-13-9-5-3-8-4-6-11(12)14-10(8)7-9/h3-7H,2H2,1H3
InChI key
LIFAQMGORKPVDH-UHFFFAOYSA-N
Application
7-乙氧基香豆素已被用于研究重组P450的功能活性。) 它还被用作 体外S-华法林7-羟基化作用和高效液相色谱(HPLC)分析的内标物。
Biochem/physiol Actions
7-乙氧基香豆素是细胞色素P450 的一种底物。
CYP2B6 的底物
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Functional characterization of human CYP2C9 allelic variants in COS-7 cells
Du H, et al.
Frontiers in Pharmacology, 7, 98-98 (2016)
Unravelling the molecular determinants of bee sensitivity to neonicotinoid insecticides
Manjon C, et al.
Current Biology, 28(7), 1137-1143 (2018)
Diansong Zhou et al.
Drug metabolism and disposition: the biological fate of chemicals, 38(7), 1015-1018 (2010-04-13)
Dog CYP2A13 and CYP2A25 were coexpressed with dog NADPH-cytochrome P450 reductase (OR) in baculovirus-infected Sf9 insect cells. CYP2A13 effectively catalyzed 7-ethoxycoumarin (7EC) deethylation and coumarin hydroxylation with apparent K(m) values of 4.8 and 2.1 microM, respectively, similar to those observed
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| E1379-1G | 04061826709313 |
| E1379-500MG | 04061833601730 |
| E1379-25MG | 04061833460986 |
| E1379-100MG | 04061833601723 |