E1379
7-乙氧基香豆素
≥99.45% (HPLC), CYP450 substrate, powder
别名:
7-乙氧基-1-苯并吡喃-2-酮
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关于此项目
经验公式（希尔记法）:
C11H10O3
CAS Number:
分子量:
190.20
Beilstein:
146200
EC 号:
MDL编号:
UNSPSC代码:
12161501
PubChem化学物质编号:
NACRES:
NA.77
Product Name
7-乙氧基香豆素,
方案
≥99.45% (HPLC)
质量水平
表单
powder
mp
88-90 °C (lit.)
溶解性
95% ethanol: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow
荧光
λex 323 nm; λem 386 nm
SMILES字符串
CCOc1ccc2C=CC(=O)Oc2c1
InChI
1S/C11H10O3/c1-2-13-9-5-3-8-4-6-11(12)14-10(8)7-9/h3-7H,2H2,1H3
InChI key
LIFAQMGORKPVDH-UHFFFAOYSA-N
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相关类别
应用
7-乙氧基香豆素已被用于研究重组P450的功能活性。) 它还被用作 体外S-华法林7-羟基化作用和高效液相色谱（HPLC）分析的内标物。
生化/生理作用
7-乙氧基香豆素是细胞色素P450 的一种底物。
CYP2B6 的底物
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
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Dog CYP2A13 and CYP2A25 were coexpressed with dog NADPH-cytochrome P450 reductase (OR) in baculovirus-infected Sf9 insect cells. CYP2A13 effectively catalyzed 7-ethoxycoumarin (7EC) deethylation and coumarin hydroxylation with apparent K(m) values of 4.8 and 2.1 microM, respectively, similar to those observed
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Toxicology in vitro : an international journal published in association with BIBRA, 22(2), 318-327 (2007-11-06)
Xanthohumol (XN), the principal prenylated flavonoid in the hop plant, Humulus lupulus L., is suggested to have cancer chemo-preventive activities. Its mechanisms of protection have been proposed to be inhibition of metabolic activation, induction of detoxifying enzymes and antioxidant activity.
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Nanomedicine (London, England), 7(9), 1365-1374 (2012-05-16)
We investigated the heterogeneity of tafluprost metabolism in primary human hepatocytes at a single-cell level by live single-cell mass spectrometry (MS). Picoliter volumes of cytoplasm were analyzed by nano-electrospray ionization MS in order to obtain single-cell metabolite profiles. The subcellular
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