recombinant
expressed in E. coli
assay
≥90% (SDS-PAGE)
form
buffered aqueous glycerol solution
mol wt
~30 kDa (14-3-3 proteins)
shipped in
dry ice
storage temp.
−20°C
Gene Information
human ... LOC646954(646954)
Biochem/physiol Actions
14-3-3 proteins are involved in a multitude of biological processes and play a regulatory role in processes such as apoptotic cell death, mitogenic signal transduction, and cell cycle control. 14-3-3η binds various proteins such as the MTLX-2 transcription factor as well as the DNA binding domain of Miz1 transcription factor. 14-3-3η also binds the glucocorticoid receptor, functioning as a positive regulator in the glucocorticoid signaling pathway. 14-3-3η is expressed and regulated in nerve cells.
Physical form
Supplied as a 0.2 μm filtered solution in 50 mM Tris-HCl, pH 7.6, 1 mM EDTA, 1 mM DTT, and 20% glycerol (w/v).
存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable