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Merck
CN

E1752

Estrone 3-(β-D-glucuronide) sodium salt

≥99% (HPLC), estrogen metabolite, powder

别名:

1,3,5(10)-Estratrien-17-one 3-glucuronide sodium salt

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关于此项目

经验公式(希尔记法):
C24H29NaO8
化学文摘社编号:
分子量:
468.47
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
51111800
MDL number:
Beilstein/REAXYS Number:
6043458
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产品名称

Estrone 3-(β-D-glucuronide) sodium salt,

InChI key

PBULYLQKWDXDFZ-QHIGSJCSSA-M

SMILES string

[Na+].[H][C@]12CC[C@]3(C)C(=O)CC[C@@]3([H])[C@]1([H])CCc4cc(O[C@@H]5O[C@@H]([C@@H](O)[C@H](O)[C@H]5O)C([O-])=O)ccc24

InChI

1S/C24H30O8.Na/c1-24-9-8-14-13-5-3-12(10-11(13)2-4-15(14)16(24)6-7-17(24)25)31-23-20(28)18(26)19(27)21(32-23)22(29)30;/h3,5,10,14-16,18-21,23,26-28H,2,4,6-9H2,1H3,(H,29,30);/q;+1/p-1/t14-,15-,16+,18+,19+,20-,21+,23-,24+;/m1./s1

sterility

non-sterile

assay

≥99% (HPLC)

form

powder

technique(s)

ELISA: suitable

solubility

water: 20 mg/mL, clear, colorless

shipped in

ambient

storage temp.

−20°C

Quality Level

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Application

Estrone 3-(β-D-glucuronide) sodium salt has been used as a standard:
  • to estimate estrone conjugate (E1Cs) from urine samples by enzyme immunoassays (EIAs)
  • to determine corticosterone metabolites from fecal and water samples by EIA
  • to estimate progesterone and estrogen levels in feces of Chinese goral by EIA

Biochem/physiol Actions

Estrone 3 glucuronide (E3G) is a urinary metabolite of estrogen. Higher levels of estrone 3 glucuronide are observed during the early onset of the fertile period of the menstrual cycle.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

法规信息

涉药品监管产品
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历史批次信息供参考:

分析证书(COA)

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Andrew H Nagel et al.
Conservation physiology, 7(1), coz074-coz074 (2019-11-19)
This study sought to develop non-invasive techniques to monitor glucocorticoids in captive Necturus as a means to correlate inter-renal gland function in relation to environmental and physiological changes. Six individually housed breeding pairs of captive Necturus beyeri were subjected to
Rebecca C Miller et al.
Clinical chemistry, 50(5), 924-932 (2004-04-24)
Specific gravity (SG) may perform as well as creatinine (CR) correction for adjusting urinary hormone concentrations, as well as offer some advantages. We compared the two methods and applied them to US and Bangladeshi specimens to evaluate their use in
Jaruwan Khonmee et al.
Theriogenology, 82(7), 997-1006 (2014-08-19)
To date, there is no information on gonadal steroidogenic activity of female goral (Naemorhedus griseus), a threatened species of Thailand. Captive goral populations have been established to produce animals for ex situ conservation and reintroduction, but as yet none are
Lateral Flow and Consumer Diagnostics
Tiplady S
The Immunoassay Handbook, 533-536 null
Leonard F Blackwell et al.
Frontiers in public health, 6, 153-153 (2018-06-16)
The patterns of a woman's normal ovarian activity can take many forms from childhood to menopause. These patterns lie on a continuum ranging from no ovarian activity to a fully fertile ovulatory cycle, but among the other defined patterns are

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