E2127
β-雌二醇3-(β-D-葡萄糖醛酸) 钠盐
≥98% (HPLC), estradiol metbolite, powder
别名:
1,3,5(10)-Estratriene-3,17β-diol 3-glucuronide, 3,17β-Dihydroxy-1,3,5(10)-estratriene 3-glucuronide
登录 查看组织和合同定价。
选择尺寸
关于此项目
线性分子式:
C24H31O8Na
化学文摘社编号:
分子量:
470.49
UNSPSC Code:
51111800
PubChem Substance ID:
NACRES:
NA.77
MDL number:
产品名称
β-雌二醇3-(β-D-葡萄糖醛酸) 钠盐,
SMILES string
[Na].CC12CCC3C(CCc4cc(OC5OC(C(O)C(O)C5O)C(O)=O)ccc34)C1CCC2O
InChI
1S/C24H32O8.Na.H/c1-24-9-8-14-13-5-3-12(10-11(13)2-4-15(14)16(24)6-7-17(24)25)31-23-20(28)18(26)19(27)21(32-23)22(29)30;;/h3,5,10,14-21,23,25-28H,2,4,6-9H2,1H3,(H,29,30);;
InChI key
JKYLXXZHJUQLMK-UHFFFAOYSA-N
sterility
non-sterile
assay
≥98% (HPLC)
form
powder
solubility
water: 10 mg/mL, clear to slightly hazy
shipped in
ambient
storage temp.
−20°C
Quality Level
Application
β-Estradiol 3-(β-D-glucuronide) sodium salt has been used in estrogen administration. It has also been used to determine the amount of two types of glucuronidated estradiols such as estradiol-3- α glucuronide and estradiol-17- β glucuronide.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
涉药品监管产品
此项目有
K S Kan et al.
The Biochemical journal, 261(1), 297-300 (1989-07-01)
By using rat liver perfusion under one-pass conditions with a single pulse of horseradish peroxidase (HRP), the biliary output of HRP was used as an indicator of paracellular permeability change caused by the cholestatic compound oestradiol 17 beta-glucuronide (E17G). Since
Aldo D Mottino et al.
The Journal of pharmacology and experimental therapeutics, 307(1), 306-313 (2003-08-02)
Estradiol-17beta-D-glucuronide (E2-17G) induces an acute but reversible inhibition of bile flow after its intravenous administration to rats, due in part to the endocytic retrieval of the canalicular multidrug resistance-associated transporter protein 2 and the bile salt export pump, transporters that
[Contraception per computer. Hormone system persona--results of studies in Germany].
G Freundl et al.
Fortschritte der Medizin, 116(9), 47-48 (1998-05-13)
M H Rae et al.
Clinica chimica acta; international journal of clinical chemistry, 176(1), 71-81 (1988-08-15)
Urinary oestrone-3-glucuronide, oestradiol-3-glucuronide, oestrone and oestradiol were measured by radioimmunoassay methods adapted for the very low levels found in postmenopausal women. Oestrogen concentrations related to creatinine in morning urine samples from ten postmenopausal women were found to correlate well with
N Kanai et al.
The American journal of physiology, 270(2 Pt 2), F326-F331 (1996-02-01)
Although substantial evidence indicates that estradiol-17 beta (E2) is conjugated to the glucuronide in the kidney and then excreted by a direct tubular secretory route and that the liver transports E2 glucuronides via carrier-mediated mechanisms, the transporters involved in these
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持