E2128
β-Estradiol 3-(β-D-glucuronide) 17-sulfate dipotassium salt
别名:
1,3,5(10)-Estratriene-3,17β-diol 3-glucuronide 17-sulfate, 3,17β-Dihydroxy-1,3,5(10)-estratriene 3-glucuronide 17-sulfate
登录 查看组织和合同定价。
选择尺寸
变更视图
关于此项目
线性分子式:
C24H30O11SK2
化学文摘社编号:
分子量:
604.75
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
51111800
MDL number:
sterility
non-sterile
Quality Level
assay
≥98% (TLC)
form
powder
solubility
water: 50 mg/mL, clear, colorless
shipped in
ambient
storage temp.
−20°C
SMILES string
[K].CC12CCC3C(CCc4cc(OC5OC(C(O)C(O)C5O)C(O)=O)ccc34)C1CCC2OS(O)(=O)=O
InChI
1S/C24H32O11S.K.H/c1-24-9-8-14-13-5-3-12(33-23-20(27)18(25)19(26)21(34-23)22(28)29)10-11(13)2-4-15(14)16(24)6-7-17(24)35-36(30,31)32;;/h3,5,10,14-21,23,25-27H,2,4,6-9H2,1H3,(H,28,29)(H,30,31,32);;
InChI key
HHYDRCVKADTNKW-UHFFFAOYSA-N
Biochem/physiol Actions
Estradiol is derived from estrogen and it exists as a conjugate as sulfate and glucuronides. This conjugation enables in bringing down the estradiol hormonal activity and aids in eliminating them through excretion.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
新产品
此项目有
H Kuhl
Climacteric : the journal of the International Menopause Society, 8 Suppl 1, 3-63 (2005-08-23)
This review comprises the pharmacokinetics and pharmacodynamics of natural and synthetic estrogens and progestogens used in contraception and therapy, with special consideration of hormone replacement therapy. The paper describes the mechanisms of action, the relation between structure and hormonal activity
B T Zhu et al.
Carcinogenesis, 19(1), 1-27 (1998-02-24)
Cytochrome P450 enzymes that metabolize estrogens are expressed in the mammary gland, uterus, brain and other target tissues for estrogen action, and this results in the formation of hydroxylated estrogens in these tissues. Estradiol metabolites formed in target tissues at
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| E2128-25MG | 04061832849836 |
| E2128-5MG | 04061832849843 |