biological source
tree bark
Quality Level
assay
≥95% (HPLC)
form
powder
shelf life
5 yr
solubility
1 M NaOH: 10 mg/mL
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
SMILES string
Oc1cc2C(=O)Oc3c(O)c(O)cc4C(=O)Oc(c1O)c2-c34
InChI
1S/C14H6O8/c15-5-1-3-7-8-4(14(20)22-11(7)9(5)17)2-6(16)10(18)12(8)21-13(3)19/h1-2,15-18H
InChI key
AFSDNFLWKVMVRB-UHFFFAOYSA-N
Gene Information
human ... CSK(1445), DYRK1A(1859), GSK3B(2932), SRC(6714)
rat ... Lyn(81515), Syk(25155)
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General description
鞣花酸是在多种水果和蔬菜中天然生成的酚酸类次级植物代谢物,通常存在于绿茶、石榴、草莓、树莓和核桃中。
Application
鞣花酸已用于:
- 基于植物乳杆菌CECT 748T研究酚酸类膳食物质的代谢机制
- 作为植物乳杆菌单宁酶高产的潜在底物
- 在荨麻酚类成分和抗氧剂活性研究中作为检测标准品
- 研究膳食鞣花酸和脂肪形成表观遗传调节之间的关系
Biochem/physiol Actions
研究发现,鞣花酸可抑制低密度脂蛋白的氧化,因这种抗氧化活性它对人心脏具有保护作用。此外,它也具有抗癌、抗纤维化、抗疟原虫、细胞凋亡和化学预防活性。
其是一种常见的植物多酚,是谷胱甘肽S-转移酶的抑制剂。可用于血浆中XIIa因子的测定。 可在血液凝固中发生接触激活。
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Detecting oral kallikrein-targeting therapy through triggered contact activation: A phase I study.
Zonne L M Hofman et al.
The Journal of allergy and clinical immunology, 146(6), 1446-1449 (2020-05-04)
Inhae Kang et al.
The Journal of nutritional biochemistry, 25(9), 946-953 (2014-06-16)
Chromatin remodeling is a key mechanism in adipocyte differentiation. However, it is unknown whether dietary polyphenols are epigenetic effectors for adiposity control. Ellagic acid (EA) is a naturally occurring polyphenol in numerous fruits and vegetables. Recently, EA-containing foods have been
Antioxidant interactions of catechin, cyanidin, caffeic acid, quercetin, and ellagic acid on human LDL oxidation
Meyer AS, et al.
Food Chemistry, 61(1-2), 71-75 (1998)
Metabolism of food phenolic acids by Lactobacillus plantarum CECT 748T
Rodriguez H, et al.
Food Chemistry, 107(4), 1393-1398 (2008)
Dong Hoon Han et al.
Anticancer research, 26(5A), 3601-3606 (2006-11-11)
Antioxidant, antiproliferative and apoptosis inducing activities of a natural polyphenolic compound, ellagic acid, were studied. DPPH radical scavenging and lipid peroxidation inhibitory activities were observed. Activities of antioxidant enzymes, superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPX) were measured
商品
DISCOVER Bioactive Small Molecules for Nitric Oxide & Cell Stress Research
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| E2250-5G | 04061835512478 |
| E2250-10G | 04061833602539 |
| E2250-1G | 04061835516001 |
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