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Merck
CN

E2535

Eprosartan mesylate

≥98% (HPLC)

别名:

Eprosartan Monomethanesulfonate, SKF-108566J, Teveten

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关于此项目

经验公式(希尔记法):
C23H24N2O4S · CH4O3S
化学文摘社编号:
分子量:
520.62
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
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产品名称

Eprosartan mesylate, ≥98% (HPLC)

InChI

1S/C23H24N2O4S.CH4O3S/c1-2-3-6-21-24-14-19(12-18(23(28)29)13-20-5-4-11-30-20)25(21)15-16-7-9-17(10-8-16)22(26)27;1-5(2,3)4/h4-5,7-12,14H,2-3,6,13,15H2,1H3,(H,26,27)(H,28,29);1H3,(H,2,3,4)/b18-12+;

SMILES string

CS(O)(=O)=O.CCCCc1ncc(\C=C(/Cc2cccs2)C(O)=O)n1Cc3ccc(cc3)C(O)=O

InChI key

DJSLTDBPKHORNY-XMMWENQYSA-N

assay

≥98% (HPLC)

form

powder

color

white to off-white

solubility

DMSO: >10 mg/mL

originator

Abbott

storage temp.

room temp

Quality Level

Gene Information

human ... AGTR1(185)

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Biochem/physiol Actions

Angiotensin II type 1 (AT1) receptor antagonist; anti-hypertensive.

Features and Benefits

This compound is featured on the Angiotensin Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Abbott. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number

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Wilco de Jager et al.
BMC immunology, 10, 52-52 (2009-09-30)
Growing knowledge about cellular interactions in the immune system, including the central role of cytokine networks, has lead to new treatments using monoclonal antibodies that block specific components of the immune system. Systemic cytokine concentrations can serve as surrogate outcome
Candesartan, an angiotensin-II receptor blocker, ameliorates insulin resistance and hepatosteatosis by reducing intracellular calcium overload and lipid accumulation.
Lee, et al.
Experimental & Molecular Medicine, 55, 910-925 (2023)

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