E2535
Eprosartan mesylate
≥98% (HPLC)
别名:
Eprosartan Monomethanesulfonate, SKF-108566J, Teveten
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关于此项目
经验公式（希尔记法）:
C23H24N2O4S · CH4O3S
化学文摘社编号:
分子量:
520.62
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
方案
≥98% (HPLC)
表单
powder
颜色
white to off-white
溶解性
DMSO: >10 mg/mL
创始人
Abbott
储存温度
room temp
SMILES字符串
CS(O)(=O)=O.CCCCc1ncc(\C=C(/Cc2cccs2)C(O)=O)n1Cc3ccc(cc3)C(O)=O
InChI
1S/C23H24N2O4S.CH4O3S/c1-2-3-6-21-24-14-19(12-18(23(28)29)13-20-5-4-11-30-20)25(21)15-16-7-9-17(10-8-16)22(26)27;1-5(2,3)4/h4-5,7-12,14H,2-3,6,13,15H2,1H3,(H,26,27)(H,28,29);1H3,(H,2,3,4)/b18-12+;
InChI key
DJSLTDBPKHORNY-XMMWENQYSA-N
基因信息
human ... AGTR1(185)
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生化/生理作用
Angiotensin II type 1 (AT1) receptor antagonist; anti-hypertensive.
特点和优势
This compound is featured on the Angiotensin Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Abbott. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Candesartan, an angiotensin-II receptor blocker, ameliorates insulin resistance and hepatosteatosis by reducing intracellular calcium overload and lipid accumulation.
Lee, et al.
Experimental & Molecular Medicine, 55, 910-925 (2023)
Wilco de Jager et al.
BMC immunology, 10, 52-52 (2009-09-30)
Growing knowledge about cellular interactions in the immune system, including the central role of cytokine networks, has lead to new treatments using monoclonal antibodies that block specific components of the immune system. Systemic cytokine concentrations can serve as surrogate outcome
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