E3140
5,8,11-Eicosatriynoic acid
≥98%
别名:
ETI
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C20H28O2
化学文摘社编号:
分子量:
300.44
UNSPSC Code:
12352202
PubChem Substance ID:
MDL number:
产品名称
5,8,11-Eicosatriynoic acid, ≥98%
InChI
1S/C20H28O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h2-8,11,14,17-19H2,1H3,(H,21,22)
SMILES string
CCCCCCCCC#CCC#CCC#CCCCC(O)=O
InChI key
OWYNLPMPYBYKJP-UHFFFAOYSA-N
assay
≥98%
form
powder
solubility
methanol: 10 mg/mL, clear, colorless to light yellow
storage temp.
−20°C
Biochem/physiol Actions
The acetylenic analog of 5,8,11-eicosatrienoic acid is an inhibitor of 12-lipoxygenase and, in MDCK cells, triggers release of Ca2+ from endoplasmic reticulum and other intracellular stores.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
An inhibitor of lipoxygenase inhibits histamine release from human basophils.
G Marone et al.
Clinical immunology and immunopathology, 17(1), 117-122 (1980-09-01)
G Marone et al.
Journal of clinical & laboratory immunology, 12(2), 111-116 (1983-10-01)
We have studied the role of arachidonic acid (AA) metabolism in the release of lysosomal enzymes (beta-glucuronidase and lysozyme) from human polymorphonuclear leukocytes (PMNs). 5,8,11,14-Eicosatetraenoic acid (ETYA), which inhibits both the cyclo-oxygenase and the lipoxygenase pathways of AA metabolism, was
Qi Wang et al.
PLoS pathogens, 17(1), e1009175-e1009175 (2021-01-12)
The zig-zag model of host-pathogen interaction describes the relative strength of defense response across a spectrum of pathogen-induced plant phenotypes. A stronger defense response results in increased resistance. Here, we investigate the strength of pathogen virulence during disease and place
G Wang et al.
Bone & joint research, 6(7), 452-463 (2017-08-03)
Osteoporosis has become an increasing concern for older people as it may potentially lead to osteoporotic fractures. This study is designed to assess the efficacy and safety of ten therapies for post-menopausal women using network meta-analysis. We conducted a systematic
J A Warner et al.
The Journal of allergy and clinical immunology, 82(3 Pt 1), 432-438 (1988-09-01)
We have characterized the effects of eight different drugs on the IgE-mediated histamine release (HR) and leukotriene C4 (LTC4R) from human basophils. Arachidonic acid analogues 5,8,11 eicosatriynoic acid and 5,8,11,15 eicosatetraynoic acid inhibit the release of both mediators in the
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持