E3149
S-Ethylisothiourea hydrobromide
≥98%
别名:
2-Ethyl-2-thiopseudourea hydrobromide
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关于此项目
经验公式（希尔记法）:
C3H8N2S · HBr
化学文摘社编号:
分子量:
185.09
UNSPSC Code:
12171500
PubChem Substance ID:
MDL number:
SMILES string
Br[H].CCSC(N)=N
assay
≥98%
storage temp.
2-8°C
Biochem/physiol Actions
Inhibitor of inducible human, endothelial and neuronal nitric oxide synthetase isozymes.
存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
188.6 °F - Solvent
flash_point_c
87 °C - Solvent
法规信息
新产品
此项目有
G J Southan et al.
British journal of pharmacology, 114(2), 510-516 (1995-01-01)
1. The induction of a calcium-independent isoform of nitric oxide (NO) synthase (iNOS) and a subsequent enhanced formation of NO has been implicated in the pathophysiology of a variety of diseases including inflammation and circulatory shock. Here we demonstrate that
E P Garvey et al.
The Journal of biological chemistry, 269(43), 26669-26676 (1994-10-28)
S-Ethylisothiourea was a potent competitive inhibitor of human nitric oxide synthase (NOS), with Ki values of 17, 36, and 29 nM for the inducible (i), endothelial (e), and neuronal (n) isozymes, respectively. Unlike some potent inhibitors of NOS, no time
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