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经验公式(希尔记法):
C18H24O3
化学文摘社编号:
分子量:
288.38
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352202
EC Number:
208-937-9
MDL number:
产品名称
16-Epiestriol, ≥93% (HPLC)
InChI key
PROQIPRRNZUXQM-UHFFFAOYSA-N
InChI
1S/C18H24O3/c1-18-7-6-13-12-5-3-11(19)8-10(12)2-4-14(13)15(18)9-16(20)17(18)21/h3,5,8,13-17,19-21H,2,4,6-7,9H2,1H3
SMILES string
CC12CCC3C(CCc4cc(O)ccc34)C1CC(O)C2O
assay
≥93% (HPLC)
form
powder
solubility
ethanol: 0.98-1.02 mg/mL, clear, colorless to faintly yellow
shipped in
ambient
storage temp.
room temp
Quality Level
Biochem/physiol Actions
16-Epiestriol, an estradiol metabolite, possesses anti-inflammatory properties but no glycogenic properties.
16-Epiestriol is found naturally in various animals, plants, and fungal yeast. It potentially inhibits the growth of colistins and carbapenem-resistant A. baumannii
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
涉药品监管产品
此项目有
Cher M Dallal et al.
Medicine and science in sports and exercise, 48(3), 439-448 (2015-10-16)
Physical activity may reduce endogenous estrogens, but few studies have assessed effects on estrogen metabolism and none have evaluated sedentary behavior in relation to estrogen metabolism. We assessed relationships between accelerometer-measured physical activity and sedentary behavior and 15 urinary estrogens
Sally B Coburn et al.
Cancer causes & control : CCC, 30(1), 75-86 (2018-12-07)
The comparability between serum, plasma, and urinary measurements of estrogen metabolites via liquid chromatography-tandem mass spectrometry (LC-MS/MS) has not been largely explored, and it is unclear if urinary LC-MS/MS measurements are suitable surrogates of circulating levels. Serum, plasma (EDTA and
Concentration of endogenous estrogens and estrogen metabolites in the NCI-60 human tumor cell lines.
Xia Xu et al.
Genome medicine, 4(4), 31-31 (2012-05-02)
Endogenous estrogens and estrogen metabolites play an important role in the pathogenesis and development of human breast, endometrial, and ovarian cancers. Increasing evidence also supports their involvement in the development of certain lung, colon and prostate cancers. In this study
Emanuela Taioli et al.
Reproductive biology and endocrinology : RB&E, 8, 93-93 (2010-08-04)
An important aspect of the link between estrogen and breast cancer is whether urinary estrogen levels are representative of the intra-tissue levels of bioavailable estrogens. This study compares 15 estrogen and estrogen metabolite levels in breast tissue and urine of
Sinosh Skariyachan et al.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases, 82, 104314-104314 (2020-04-09)
The current study aimed to identify putative drug targets of multidrug resistant Acinetobacter baumannii (MDRAb) and study the therapeutic potential of natural epiestriol-16 by computer aided virtual screening and in vitro studies. The clinical isolates (n = 5) showed extreme dug resistance
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