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Merck
CN

E3625

Sigma-Aldrich

16-Epiestriol

≥93% (HPLC), estradiol metbolite, powder

别名:

1,3,5(10)-Estratriene-3,16β,17β-triol, 16β-Hydroxy-17β-estradiol, 3,16β,17β-Trihydroxy-1,3,5(10)-estratriene

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关于此项目

经验公式(希尔记法):
C18H24O3
化学文摘社编号:
分子量:
288.38
EC 号:
MDL编号:
UNSPSC代码:
12352202
PubChem化学物质编号:
NACRES:
NA.77
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产品名称

16-Epiestriol, ≥93% (HPLC)

质量水平

方案

≥93% (HPLC)

表单

powder

溶解性

ethanol: 0.98-1.02 mg/mL, clear, colorless to faintly yellow

运输

ambient

储存温度

room temp

SMILES字符串

CC12CCC3C(CCc4cc(O)ccc34)C1CC(O)C2O

InChI

1S/C18H24O3/c1-18-7-6-13-12-5-3-11(19)8-10(12)2-4-14(13)15(18)9-16(20)17(18)21/h3,5,8,13-17,19-21H,2,4,6-7,9H2,1H3

InChI key

PROQIPRRNZUXQM-UHFFFAOYSA-N

生化/生理作用

16-Epiestriol is found naturally in various animals, plants, and fungal yeast. It potentially inhibits the growth of colistins and carbapenem-resistant A. baumannii
16-Epiestriol, an estradiol metabolite, possesses anti-inflammatory properties but no glycogenic properties.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

涉药品监管产品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Ju-Yeon Moon et al.
BMC clinical pathology, 13(1), 25-25 (2013-10-26)
Estrogen metabolism may be associated with the pathophysiological development of papillary thyroid carcinoma (PTC). To evaluate the differential estrogen metabolism between benign and malignant PTCs, estrogen profiling by gas chromatography-mass spectrometry was applied to urine samples from postmenopausal patients with
Xiaoguang Sunny Li et al.
Talanta, 178, 464-472 (2017-11-16)
Accurate quantitation of estrogens (i.e, estrone (E1), estradiol (E2) and estriol (E3)) is valuable for clinical assessment of human health and disease. Alterations in estrogen levels have been implicated in numerous pathological conditions. However, inadequacies in sensitivity and specificity, cumbersome
Xia Xu et al.
Genome medicine, 4(4), 31-31 (2012-05-02)
Endogenous estrogens and estrogen metabolites play an important role in the pathogenesis and development of human breast, endometrial, and ovarian cancers. Increasing evidence also supports their involvement in the development of certain lung, colon and prostate cancers. In this study
Sinosh Skariyachan et al.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases, 82, 104314-104314 (2020-04-09)
The current study aimed to identify putative drug targets of multidrug resistant Acinetobacter baumannii (MDRAb) and study the therapeutic potential of natural epiestriol-16 by computer aided virtual screening and in vitro studies. The clinical isolates (n = 5) showed extreme dug resistance
Jodie M Fleming et al.
BMC medicine, 8, 27-27 (2010-05-25)
Breast cancer studies frequently focus on the role of the tumor microenvironment in the promotion of cancer; however, the influence of the normal breast microenvironment on cancer cells remains relatively unknown. To investigate the role of the normal breast microenvironment

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