E3750
17-Epiestriol
别名:
1,3,5(10)-Estratriene-3,16α,17α-triol, 16α-Hydroxy-17α-estradiol, 3,16α,17α-Trihydroxy-1,3,5(10)-estratriene
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关于此项目
经验公式（希尔记法）:
C18H24O3
化学文摘社编号:
分子量:
288.38
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Form:
powder
Assay:
≥98.00% (TLC)
InChI
1S/C18H24O3/c1-18-7-6-13-12-5-3-11(19)8-10(12)2-4-14(13)15(18)9-16(20)17(18)21/h3,5,8,13-17,19-21H,2,4,6-7,9H2,1H3/t13?,14?,15?,16-,17-,18?/m1/s1
SMILES string
CC12CCC3C(CCc4cc(O)ccc34)C1C[C@@H](O)[C@H]2O
InChI key
PROQIPRRNZUXQM-CKMBUZLOSA-N
sterility
non-sterile
assay
≥98.00% (TLC)
form
powder
technique(s)
inhibition assay: suitable
color
off-white to yellow
solubility
chloroform: methanol (1:1): 9.80-10.20 mg/mL, clear, colorless to faintly yellow
shipped in
ambient
storage temp.
room temp
Quality Level
Biochem/physiol Actions
17-epiestriol is an estradiol metabolite and a selective estrogen receptor (ER) beta agonist.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
Carien van der Berg et al.
Analytical biochemistry, 590, 113531-113531 (2019-12-06)
An imbalance in the estrogen metabolism has been associated with an increased risk of breast cancer development. Evaluation of the estrogen biotransformation capacity requires monitoring of various estrogen metabolites. Up to now, only some estrogen metabolites could be measured in
Antonio Cano et al.
Menopause (New York, N.Y.), 19(10), 1130-1139 (2012-08-24)
The aim of this study was to evaluate the efficacy and safety of a new low-concentration estriol formulation (0.005% estriol vaginal gel), providing an ultra low dose of estriol per application (50 μg), for the local treatment of postmenopausal vaginal
Krishna Lamichhane et al.
Journal of environmental monitoring : JEM, 14(10), 2557-2565 (2012-08-30)
Elevated concentrations of estrogens in natural waters pose a significant threat to public health and aquatic ecosystems. Both natural (estrone, 17β-estradiol and estriol) and synthetic (17α ethynylestradiol) estrogens, ubiquitous in wastewater effluents and receiving waters, have been shown to affect
Maya Frank et al.
Prenatal diagnosis, 33(2), 191-195 (2013-01-08)
To compare the profile of mid gestation triple test serum markers between a cohort of women with history of pregnancy complications with hereditary versus acquired thrombophilia. All were treated with low molecular weight heparin (LMWH) prior to 12 weeks' gestation.
Tasneem Siyam et al.
Maturitas, 74(2), 196-202 (2012-12-26)
The aim of this study was to assess pharmacists' beliefs about bioidentical hormone therapy (BHT) and to identify factors influencing these beliefs. This was a cross-sectional survey of pharmacists. An email invitation to participate in the online survey was sent
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