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Merck
CN

E3750

17-Epiestriol

别名:

1,3,5(10)-Estratriene-3,16α,17α-triol, 16α-Hydroxy-17α-estradiol, 3,16α,17α-Trihydroxy-1,3,5(10)-estratriene

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关于此项目

经验公式(希尔记法):
C18H24O3
化学文摘社编号:
分子量:
288.38
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
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无菌性

non-sterile

质量水平

方案

≥98.00% (TLC)

表单

powder

技术

inhibition assay: suitable

颜色

off-white to yellow

溶解性

chloroform: methanol (1:1): 9.80-10.20 mg/mL, clear, colorless to faintly yellow

运输

ambient

储存温度

room temp

SMILES字符串

CC12CCC3C(CCc4cc(O)ccc34)C1C[C@@H](O)[C@H]2O

InChI

1S/C18H24O3/c1-18-7-6-13-12-5-3-11(19)8-10(12)2-4-14(13)15(18)9-16(20)17(18)21/h3,5,8,13-17,19-21H,2,4,6-7,9H2,1H3/t13?,14?,15?,16-,17-,18?/m1/s1

InChI key

PROQIPRRNZUXQM-CKMBUZLOSA-N

生化/生理作用

17-epiestriol is an estradiol metabolite and a selective estrogen receptor (ER) beta agonist.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

新产品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Carien van der Berg et al.
Analytical biochemistry, 590, 113531-113531 (2019-12-06)
An imbalance in the estrogen metabolism has been associated with an increased risk of breast cancer development. Evaluation of the estrogen biotransformation capacity requires monitoring of various estrogen metabolites. Up to now, only some estrogen metabolites could be measured in
Marcelo O Dietrich et al.
Trends in neurosciences, 36(2), 65-73 (2013-01-16)
The past 20 years witnessed an enormous leap in understanding of the central regulation of whole-body energy metabolism. Genetic tools have enabled identification of the region-specific expression of peripheral metabolic hormone receptors and have identified neuronal circuits that mediate the
Mitsuhiro Ueda et al.
Enzyme and microbial technology, 51(6-7), 402-407 (2012-10-09)
A protein with strong removal activity against the natural estrogen estriol was purified from a culture supernatant of Pleurotus eryngii var. tuoliensis C.J. Mou. The protein was characterized as a laccase and had a molecular mass of 60kDa on SDS-PAGE.
Antonio Cano et al.
Menopause (New York, N.Y.), 19(10), 1130-1139 (2012-08-24)
The aim of this study was to evaluate the efficacy and safety of a new low-concentration estriol formulation (0.005% estriol vaginal gel), providing an ultra low dose of estriol per application (50 μg), for the local treatment of postmenopausal vaginal
Maya Frank et al.
Prenatal diagnosis, 33(2), 191-195 (2013-01-08)
To compare the profile of mid gestation triple test serum markers between a cohort of women with history of pregnancy complications with hereditary versus acquired thrombophilia. All were treated with low molecular weight heparin (LMWH) prior to 12 weeks' gestation.

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