E5126
还原胆烷醇酮
≥98% (TLC), testosterone metabolite, powder
别名:
3α-羟基-5β-雄甾烷-17-酮, 5β-雄酮, 还原尿睾酮
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关于此项目
经验公式（希尔记法）:
C19H30O2
化学文摘社编号:
分子量:
290.44
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
Beilstein/REAXYS Number:
2217625
产品名称
还原胆烷醇酮,
InChI
1S/C19H30O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h12-16,20H,3-11H2,1-2H3/t12-,13-,14+,15+,16+,18+,19+/m1/s1
SMILES string
C[C@]12CC[C@@H](O)C[C@H]1CC[C@@H]3[C@@H]2CC[C@@]4(C)[C@H]3CCC4=O
InChI key
QGXBDMJGAMFCBF-BNSUEQOYSA-N
assay
≥98% (TLC)
form
powder
drug control
regulated under CDSA - not available from Sigma-Aldrich Canada
solubility
chloroform: 9.80-10.20 mg/mL, clear, colorless
shipped in
ambient
storage temp.
room temp
Quality Level
Gene Information
human ... SERPINA6(866)
rat ... Gabra1(29705), Gabra2(29706), Gabrg2(29709)
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signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Repr. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
Clemens Kamrath et al.
The Journal of clinical endocrinology and metabolism, 97(3), E367-E375 (2011-12-16)
17-Hydroxyprogesterone (17-OHP) can be converted to dihydrotestosterone (DHT) via an alternative "backdoor" route that bypasses the conventional intermediates androstenedione and testosterone. In this backdoor pathway, 17-OHP is converted to 5α-pregnane-3α,17α-diol-20-one (pdiol), which is an excellent substrate for the 17,20 lyase
Clinical implications of the 5α-androstanedione pathway for castration-resistant prostate cancer.
Nima Sharifi
Future oncology (London, England), 7(11), 1239-1241 (2011-11-03)
André Ganswindt et al.
Physiological and biochemical zoology : PBZ, 85(2), 194-199 (2012-03-16)
Biologically inert material in feces may confound interpretations of noninvasive fecal endocrine data, because it may induce variance related to differences in foraging behavior rather than to differences in endocrine activity. We evaluated two different enzyme immunoassays (EIAs) for the
Mihai Gheorghiade et al.
Discovery medicine, 12(63), 141-151 (2011-09-01)
Heart failure (HF) patients are a medically complex and heterogeneous population with multiple cardiac and non-cardiac comorbidities. Although there are a multitude of etiologic substrates and initiating and amplifying mechanisms contributing to disease progression, these pathophysiologic processes ultimately all lead
Istaroxime: is the remedy better than the disease?: Editorial to: "Chronic istaroxine improves cardiac function and heart rate variability in cardiomyopathic hamsters" by Pietro Lo Giudice et al.
Dimitrios Farmakis et al.
Cardiovascular drugs and therapy, 25(2), 115-117 (2011-04-13)
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