E5139
DL-乙硫氨基酪酸
≥95% (TLC)
别名:
DL-2-氨基-4-(乙硫基)丁酸
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线性分子式:
C2H5SCH2CH2CH(NH2)COOH
化学文摘社编号:
分子量:
163.24
Beilstein/REAXYS Number:
1722529
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
200-647-0
MDL number:
产品名称
DL-乙硫氨基酪酸, ≥95% (TLC)
InChI key
GGLZPLKKBSSKCX-UHFFFAOYSA-N
InChI
1S/C6H13NO2S/c1-2-10-4-3-5(7)6(8)9/h5H,2-4,7H2,1H3,(H,8,9)
SMILES string
CCSCCC(N)C(O)=O
assay
≥95% (TLC)
form
powder
color
white to off-white
mp
269 °C
application(s)
cell analysis
storage temp.
−20°C
Quality Level
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Application
- 用超氧化物歧化酶活性衡量牛摄入乙硫氨酸后的肝脏氧化应激。：该研究通过测量超氧化物歧化酶的活性，评估了牛服用乙硫氨酸后引起的肝脏氧化应激。研究结果表明，肝脏存在明显的氧化反应，突出了DL-乙硫氨酸在研究肝脏氧化机制中的作用（Abd Ellah et al., 2009）。
Biochem/physiol Actions
DL-乙硫氨酸是抗甲基化剂 L-乙硫氨酸及其对映体 D-乙硫氨酸的外消旋混合物。DL-乙硫氨酸作为膳食补充剂在体内加速胆管癌的发生 。DL-乙硫氨酸用于诱导肝脏氧化应激，研究抗氧化酶和谷胱甘肽等化合物的水平和活性。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
Janeli Viil et al.
Scientific reports, 7, 40322-40322 (2017-01-14)
Cells with slow proliferation kinetics that retain the nuclear label over long time periods-the label-retaining cells (LRCs)-represent multipotent stem cells in a number of adult tissues. Since the identity of liver LRCs (LLRCs) had remained elusive we utilized a genetic
Mami Furukawa et al.
Anticancer research, 29(10), 4047-4050 (2009-10-23)
To evaluate an involvement of LKB1 gene alteration during pancreatic carcinogenesis, mutations in the LKB1 gene in hamster pancreatic duct adenocarcinomas (PDAs) induced by N-nitrosobis(2-oxopropyl)amine (BOP) were investigated. Female Syrian golden hamsters received 30 mg/kg of BOP followed by repeated
Muneyoshi Kanai et al.
Journal of bioscience and bioengineering, 123(1), 8-14 (2016-08-28)
Sake yeasts are ideally suited for sake making, producing higher levels of ethanol, proliferating at lower temperatures, and producing greater levels of various aromatic components and nutrients than laboratory yeasts. To elucidate the mechanism underlying S-adenosylmethionine (SAM) accumulation in sake
Miku Hirane et al.
Molecular carcinogenesis, 55(11), 1573-1583 (2015-09-18)
Lysophosphatidic acid (LPA) signaling via LPA receptors (LPA1 to LPA6 ) mediates a variety of cellular functions, including cell motility. In the present study, we investigated the effects of LPA receptors on cell motile activity during multi-stage hepatocarcinogenesis in rat
Mahmoud R Abd Ellah et al.
Veterinary journal (London, England : 1997), 182(2), 336-341 (2008-07-01)
The goal of this study was to assess if oxidative stress, as measured by alterations in the concentrations of antioxidant enzymes in the liver and erythrocytes of cattle, could be induced following dl-ethionine administration. Whole blood, serum and liver biopsy
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