E5139
DL-乙硫氨基酪酸
≥95% (TLC)
别名:
DL-2-氨基-4-(乙硫基)丁酸
产品名称
DL-乙硫氨基酪酸, ≥95% (TLC)
方案
≥95% (TLC)
表单
powder
颜色
white to off-white
mp
269 °C
应用
cell analysis
储存温度
−20°C
SMILES字符串
CCSCCC(N)C(O)=O
InChI
1S/C6H13NO2S/c1-2-10-4-3-5(7)6(8)9/h5H,2-4,7H2,1H3,(H,8,9)
InChI key
GGLZPLKKBSSKCX-UHFFFAOYSA-N
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相关类别
应用
- 用超氧化物歧化酶活性衡量牛摄入乙硫氨酸后的肝脏氧化应激。：该研究通过测量超氧化物歧化酶的活性，评估了牛服用乙硫氨酸后引起的肝脏氧化应激。研究结果表明，肝脏存在明显的氧化反应，突出了DL-乙硫氨酸在研究肝脏氧化机制中的作用（Abd Ellah et al., 2009）。
生化/生理作用
DL-乙硫氨酸是抗甲基化剂 L-乙硫氨酸及其对映体 D-乙硫氨酸的外消旋混合物。DL-乙硫氨酸作为膳食补充剂在体内加速胆管癌的发生 。DL-乙硫氨酸用于诱导肝脏氧化应激，研究抗氧化酶和谷胱甘肽等化合物的水平和活性。
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Yingying Liu et al.
Stem cells (Dayton, Ohio), 33(12), 3569-3580 (2015-06-03)
Upregulation of osteopontin (OPN) has been found in hepatic progenitor cells (HPCs) in several liver diseases with portal biliary proliferation. Here, we investigated the role of HPC-derived autocrine OPN in regulating HPC expansion, migration, and hepatocarcinogenesis in mice. Five-week-old, weighing
Tirthadipa Pradhan-Sundd et al.
Gastroenterology, 155(4), 1218-1232 (2018-07-03)
Liver fibrosis, hepatocellular necrosis, inflammation, and proliferation of liver progenitor cells are features of chronic liver injury. Mouse models have been used to study the end-stage pathophysiology of chronic liver injury. However, little is known about differences in the mechanisms
Janeli Viil et al.
Scientific reports, 7, 40322-40322 (2017-01-14)
Cells with slow proliferation kinetics that retain the nuclear label over long time periods-the label-retaining cells (LRCs)-represent multipotent stem cells in a number of adult tissues. Since the identity of liver LRCs (LLRCs) had remained elusive we utilized a genetic
Mahmoud R Abd Ellah et al.
Veterinary journal (London, England : 1997), 182(2), 336-341 (2008-07-01)
The goal of this study was to assess if oxidative stress, as measured by alterations in the concentrations of antioxidant enzymes in the liver and erythrocytes of cattle, could be induced following dl-ethionine administration. Whole blood, serum and liver biopsy
Muneyoshi Kanai et al.
Journal of bioscience and bioengineering, 123(1), 8-14 (2016-08-28)
Sake yeasts are ideally suited for sake making, producing higher levels of ethanol, proliferating at lower temperatures, and producing greater levels of various aromatic components and nutrients than laboratory yeasts. To elucidate the mechanism underlying S-adenosylmethionine (SAM) accumulation in sake
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