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E5156

盐酸依匹斯汀盐酸盐

Name: 盐酸依匹斯汀 盐酸盐
Brand: SIGMA

≥98% (HPLC), H1 histamine receptor antagonist, solid

别名:

9,13b-Dihydro-1H-dibenz[cf]imidazo[1,5-a]azepine hydrochloride, WAL-801Cl

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关于此项目

经验公式（希尔记法）:

C₁₆H₁₅N₃ · HCl

化学文摘社编号:

108929-04-0

分子量:

285.77

UNSPSC Code:

12352200

PubChem Substance ID:

24894608

NACRES:

NA.77

MDL number:

MFCD00933434

Assay:

≥98% (HPLC)

Form:

solid

Storage condition:

desiccated

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属性

产品名称

盐酸依匹斯汀盐酸盐, ≥98% (HPLC), solid

Quality Segment

100

assay

≥98% (HPLC)

form

solid

storage condition

desiccated

color

white

solubility

H₂O: 38 mg/mL

originator

Boehringer Ingelheim

storage temp.

2-8°C

SMILES string

Cl[H].NC1=NCC2N1c3ccccc3Cc4ccccc24

InChI

1S/C16H15N3.ClH/c17-16-18-10-15-13-7-3-1-5-11(13)9-12-6-2-4-8-14(12)19(15)16;/h1-8,15H,9-10H2,(H2,17,18);1H

InChI key

VKXSGUIOOQPGAF-UHFFFAOYSA-N

Gene Information

human ... HRH1(3269)

说明

General description

Epinastine has antihistamine functions. In mast cells, it may modulate cytokine and chemokine production. In dendritic cells, it controls T helper cell mediated immune response. Epinastine hydrochloride does not traverse the brain barrier. Oral dosage of epinastine hydrochloride is prescribed for children with sleep-disordered breathing (SDB) and nasal inflammation. Ophthalmic solution of epinastine is effective for allergic conjunctivitis.

Biochem/physiol Actions

Epinastine hydrochloride is a non-sedating H1 histamine receptor antagonist.

Features and Benefits

This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Boehringer Ingelheim. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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pictograms

GHS06

signalword

Danger

hcodes

H301

pcodes

P264 - P270 - P301 + P310 - P405 - P501

Hazard Classifications

Acute Tox. 3 Oral

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

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全球贸易项目编号

货号	GTIN
E5156-10MG	04061832071954
E5156-50MG	04061832071961