E5156
盐酸依匹斯汀 盐酸盐
≥98% (HPLC), H1 histamine receptor antagonist, solid
别名:
9,13b-Dihydro-1H-dibenz[cf]imidazo[1,5-a]azepine hydrochloride, WAL-801Cl
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关于此项目
经验公式（希尔记法）:
C16H15N3 · HCl
化学文摘社编号:
分子量:
285.77
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
solid
Storage condition:
desiccated
产品名称
盐酸依匹斯汀 盐酸盐, ≥98% (HPLC), solid
Quality Segment
assay
≥98% (HPLC)
form
solid
storage condition
desiccated
color
white
solubility
H2O: 38 mg/mL
originator
Boehringer Ingelheim
storage temp.
2-8°C
SMILES string
Cl[H].NC1=NCC2N1c3ccccc3Cc4ccccc24
InChI
1S/C16H15N3.ClH/c17-16-18-10-15-13-7-3-1-5-11(13)9-12-6-2-4-8-14(12)19(15)16;/h1-8,15H,9-10H2,(H2,17,18);1H
InChI key
VKXSGUIOOQPGAF-UHFFFAOYSA-N
Gene Information
human ... HRH1(3269)
General description
Epinastine has antihistamine functions. In mast cells, it may modulate cytokine and chemokine production. In dendritic cells, it controls T helper cell mediated immune response. Epinastine hydrochloride does not traverse the brain barrier. Oral dosage of epinastine hydrochloride is prescribed for children with sleep-disordered breathing (SDB) and nasal inflammation. Ophthalmic solution of epinastine is effective for allergic conjunctivitis.
Biochem/physiol Actions
Epinastine hydrochloride is a non-sedating H1 histamine receptor antagonist.
Features and Benefits
This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Boehringer Ingelheim. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
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signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges