E6511
乙二胺四乙酸 四钠盐 二水合物
BioReagent, suitable for cell culture, 98.5-102.0%
别名:
EDTA 四钠盐, 乙二胺四乙酸四钠盐 二水合物, 依地酸钙钠
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线性分子式:
(NaOOCCH2)2NCH2CH2N(CH2COONa)2 · 2H2O
化学文摘社编号:
分子量:
416.20
UNSPSC Code:
12352204
NACRES:
NA.75
PubChem Substance ID:
EC Number:
200-573-9
Beilstein/REAXYS Number:
3861753
MDL number:
产品名称
乙二胺四乙酸 四钠盐 二水合物, BioReagent, suitable for cell culture, 98.5-102.0%
InChI
1S/C10H16N2O8.4Na.2H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;;;2*1H2/q;4*+1;;/p-4
InChI key
KSYNLCYTMRMCGG-UHFFFAOYSA-J
SMILES string
O.O.[Na+].[Na+].[Na+].[Na+].[O-]C(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC([O-])=O
product line
BioReagent
assay
98.5-102.0%
form
powder
technique(s)
cell culture | mammalian: suitable
solubility
H2O: 160 mg/mL
shipped in
ambient
storage temp.
room temp
Quality Level
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Application
乙二胺四乙酸四钠盐二水合物用作：
- 螯合剂，从月经血中分离人子宫内膜干细胞/基质细胞（hEnSCs）
- 螯合剂，分离动物细胞和睾丸细胞
- 螯合剂，培养神经干细胞
Biochem/physiol Actions
乙二胺四乙酸(EDTA)用于消除痕量重金属对酶的抑制作用，并抑制需要二价阳离子作为辅因子的酶。
General description
乙二胺四乙酸（EDTA）是金属离子螯合剂。是一种取代二胺，具有抗菌活性。脱色过程中，EDTA消除铁离子、铜离子和锰离子产生的不良影响。可阻止细胞分裂，叶绿素合成和藻类生物量产生。EDTA 是金属蛋白酶的抑制剂。具有抗凝剂的特性。
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - STOT RE 2
target_organs
Respiratory Tract
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Onofre J, et al.
Reproductive Biomedicine Online, 37(1), 6-17 (2018)
Modulation of matrix metalloproteinase activity by EDTA prevents posterior capsular opacification
Hazra S, et al.
Molecular Vision, 18(6), 1701-1701 (2012)
Accurate Results in the Clinical Laboratory: A Guide to Error Detection and Correction (2013)
Human Endometrial Stem Cell Isolation from Endometrium and Menstrual Blood
Tavakol S, et al.
Bio-protocol, 8(2) (2018)
Mary L Bath
PloS one, 5(2), e9387-e9387 (2010-03-03)
In vitro fertilization (IVF) of eggs by frozen and thawed C57BL/6J mouse sperm is inhibited by dead sperm and enhanced by preincubation of the sperm in calcium-free medium. In other species, the presence of sperm killed by freezing and thawing
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