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Merck
CN

E6527

Sigma-Aldrich

可溶性弹性蛋白 来源于牛颈部韧带

salt-free, lyophilized powder

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化学文摘社编号:
EC 号:
MDL编号:
UNSPSC代码:
12352202
NACRES:
NA.61
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生物来源

bovine neck ligament

质量水平

表单

salt-free, lyophilized powder

技术

UV/Vis spectroscopy: suitable

UniProt登记号

储存温度

2-8°C

SMILES字符串

N1([C@@H](CCC1)C(=O)NC)C(=O)[C@@H](NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)C)CC(C)C)[C@H](CC)C)C(C)C

InChI

1S/C27H48N6O6/c1-9-17(6)23(32-24(36)19(13-15(2)3)30-18(7)34)26(38)29-14-21(35)31-22(16(4)5)27(39)33-12-10-11-20(33)25(37)28-8/h15-17,19-20,22-23H,9-14H2,1-8H3,(H,28,37)(H,29,38)(H,30,34)(H,31,35)(H,32,36)/t17-,19-,20-,22-,23-/m0/s1

InChI key

DPUYCSDGMSDKKV-MKBYFEBXSA-N

基因信息

cow ... ELN(280781)

一般描述

采用 Partrige 等的方法制备水溶性粉末。

应用

如 Keller 和 Mandi 所述,适用于测定弹性蛋白溶解活性。
弹性蛋白是一种结构蛋白,已用于研究慢性阻塞性肺疾病(COPD)。它可以用来研究为什么COPD患者缺乏这些蛋白的修复。
由于其增溶的几种策略,目前发现高度稳定且具有血液相容性的蛋白质可用于构建生物材料。

生化/生理作用

负责许多组织弹性的蛋白质。它在血管中尤其重要,因为它占干组织重量的 50%。

免责声明

在 pH 5.0 和 37°C 条件下,形成凝聚层

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

监管及禁止进口产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Felix Cleemann et al.
Analytical chemistry, 80(11), 4170-4174 (2008-04-25)
A novel fluorescence polarization assay based on the natural fluorophore epicocconone has been developed. This assay allows the rapid and accurate determination of enzyme kinetic parameters as well as inhibition constants through the measurement of fluorescence anisotropy on the actual
Mervyn J Merrilees et al.
Respiratory research, 9, 41-41 (2008-05-20)
COPD is characterised by loss of alveolar elastic fibers and by lack of effective repair. Elastic fibers are assembled at cell surfaces by elastin binding protein (EBP), a molecular chaperone whose function can be reversibility inhibited by chondroitin sulphate of
Wolfgang G Mouton et al.
Swiss medical weekly, 143, w13755-w13755 (2013-02-28)
The ultrastructure of venous valves and walls in chronic venous disease was investigated. Consecutive patients were categorised into one of three groups (group A: patients with C1 venous disease in accordance with CEAP (Clinical severity, Etiology, Anatomy, Pathophysiology); group B:
Heath B Henninger et al.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 31(8), 1226-1233 (2013-04-05)
Elastin is a structural protein that provides resilience to biological tissues. We examined the contributions of elastin to the quasi-static tensile response of porcine medial collateral ligament through targeted disruption of the elastin network with pancreatic elastase. Elastase concentration and
Andrea Heinz et al.
Biochimica et biophysica acta, 1830(4), 2994-3004 (2013-02-05)
Elastin is a vital protein and the major component of elastic fibers which provides resilience to many vertebrate tissues. Elastin's structure and function are influenced by extensive cross-linking, however, the cross-linking pattern is still unknown. Small peptides containing reactive allysine

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