产品名称
可溶性弹性蛋白 来源于牛颈部韧带, salt-free, lyophilized powder
SMILES string
N1([C@@H](CCC1)C(=O)NC)C(=O)[C@@H](NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)C)CC(C)C)[C@H](CC)C)C(C)C
InChI key
DPUYCSDGMSDKKV-MKBYFEBXSA-N
InChI
1S/C27H48N6O6/c1-9-17(6)23(32-24(36)19(13-15(2)3)30-18(7)34)26(38)29-14-21(35)31-22(16(4)5)27(39)33-12-10-11-20(33)25(37)28-8/h15-17,19-20,22-23H,9-14H2,1-8H3,(H,28,37)(H,29,38)(H,30,34)(H,31,35)(H,32,36)/t17-,19-,20-,22-,23-/m0/s1
biological source
bovine neck ligament
form
salt-free, lyophilized powder
technique(s)
UV/Vis spectroscopy: suitable
UniProt accession no.
storage temp.
2-8°C
Quality Level
Gene Information
cow ... ELN(280781)
Disclaimer
在 pH 5.0 和 37°C 条件下，形成凝聚层
General description
采用 Partrige 等的方法制备水溶性粉末。
Application
如 Keller 和 Mandi 所述，适用于测定弹性蛋白溶解活性。
弹性蛋白是一种结构蛋白，已用于研究慢性阻塞性肺疾病（COPD）。它可以用来研究为什么COPD患者缺乏这些蛋白的修复。
由于其增溶的几种策略，目前发现高度稳定且具有血液相容性的蛋白质可用于构建生物材料。
Biochem/physiol Actions
负责许多组织弹性的蛋白质。它在血管中尤其重要，因为它占干组织重量的 50%。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
监管及禁止进口产品
此项目有
Felix Cleemann et al.
Analytical chemistry, 80(11), 4170-4174 (2008-04-25)
A novel fluorescence polarization assay based on the natural fluorophore epicocconone has been developed. This assay allows the rapid and accurate determination of enzyme kinetic parameters as well as inhibition constants through the measurement of fluorescence anisotropy on the actual
Mervyn J Merrilees et al.
Respiratory research, 9, 41-41 (2008-05-20)
COPD is characterised by loss of alveolar elastic fibers and by lack of effective repair. Elastic fibers are assembled at cell surfaces by elastin binding protein (EBP), a molecular chaperone whose function can be reversibility inhibited by chondroitin sulphate of
Zhongyuan Sun et al.
Journal of the American Chemical Society, 135(9), 3675-3679 (2013-02-07)
The chimeric proteins, silk-elastin-like protein polymers (SELPs), consist of repeating units of silk and elastin to retain the mechanical strength of silk, while incorporating the dynamic environmental sensitivity of elastin. A retinal-modified SELP was prepared, modified, and studied for photodynamic
A Panagopoulou et al.
Biochimica et biophysica acta, 1834(6), 977-988 (2013-03-27)
Dynamics of uncrystallized water and protein was studied in hydrated pellets of the fibrous protein elastin in a wide hydration range (0 to 23wt.%), by differential scanning calorimetry (DSC), thermally stimulated depolarization current technique (TSDC) and dielectric relaxation spectroscopy (DRS).
Stefanie Michael et al.
PloS one, 8(3), e57741-e57741 (2013-03-08)
Tissue engineering plays an important role in the production of skin equivalents for the therapy of chronic and especially burn wounds. Actually, there exists no (cellularized) skin equivalent which might be able to satisfactorily mimic native skin. Here, we utilized
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