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About This Item
经验公式（希尔记法）:
C24H30O6
CAS Number:
分子量:
414.49
MDL编号:
UNSPSC代码:
51111800
PubChem化学物质编号:
NACRES:
NA.77
Product Name
Eplerenone, ≥98% (HPLC)
质量水平
方案
≥98% (HPLC)
表单
powder
颜色
white to beige
溶解性
DMSO: 2 mg/mL, clear (warmed)
H2O: insoluble
储存温度
2-8°C
SMILES字符串
O1[C@]32[C@H]1C[C@@]4([C@@]6(OC(=O)CC6)CC[C@H]4[C@@H]3[C@@H](CC5=CC(=O)CC[C@@]52C)C(=O)OC)C
InChI
1S/C24H30O6/c1-21-7-4-14(25)10-13(21)11-15(20(27)28-3)19-16-5-8-23(9-6-18(26)30-23)22(16,2)12-17-24(19,21)29-17/h10,15-17,19H,4-9,11-12H2,1-3H3/t15-,16+,17-,19+,21+,22+,23-,24-/m1/s1
InChI key
JUKPWJGBANNWMW-VWBFHTRKSA-N
基因信息
human ... NR3C2(4306)
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一般描述
Eplerenone is an aldosterone blocker, which particularly blocks mineralocorticoid receptor. It reduces cardiovascular risk in patients following acute myocardial infarction. Eplerenone is used for treating hypertension and central serous retinopathy. It exhibits potassium sparing diuretic effect.
应用
Eplerenone has been used in quantitative real time (RT-qPCR) or western blotting assays.
生化/生理作用
Eplerenone is an aldosterone antagonist more specific for the mineralocorticoid receptor than spironolactone (S3378), having lower affinity for progesterone, androgen, and glucocorticoid receptors.
Eplerenone is an aldosterone antagonist.
特点和优势
This compound is featured on the Nuclear Receptors (Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
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