Merck
CN
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文件

E7006

Sigma-Aldrich

顺式-5,8,11,14,17-二十碳五烯酸

≥85%, liquid

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别名:
EPA, 二十碳五烯酸
线性分子式:
CH3(CH2CH=CH)5(CH2)3CO2H
CAS号:
10417-94-4
分子量:
302.45
Beilstein:
1714433
MDL编号:
MFCD00065716
PubChem化学物质编号:
24894640
NACRES:
NA.25

生物来源

fish oil

检测方案

≥85%

形式

liquid

折射率

n20/D 1.4977 (lit.)

mp

−54-−53 °C (lit.)

密度

0.943 g/mL at 25 °C (lit.)

官能团

carboxylic acid

脂质类型

omega FAs

运输

ambient

储存温度

−20°C

SMILES字符串

CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCC(O)=O

InChI

1S/C20H30O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h3-4,6-7,9-10,12-13,15-16H,2,5,8,11,14,17-19H2,1H3,(H,21,22)/b4-3-,7-6-,10-9-,13-12-,16-15-

InChI key

JAZBEHYOTPTENJ-JLNKQSITSA-N

基因信息

mouse ... Pparg(19016)

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生化/生理作用

5-脂氧合酶抑制剂；减少凝血噁烷 A2 生成。

储存分类代码

10 - Combustible liquids

WGK

WGK 3

闪点(°F)

200.1 °F - closed cup

闪点(°C)

93.4 °C - closed cup

个人防护装备

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

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Wendy L Hall et al.
The Journal of nutrition, 138(2), 287-291 (2008-01-22)
Diets rich in eicosapentaenoic acid [EPA; 20:5(n-3)] are associated with decreased arterial stiffness, but postprandial effects on vascular function are unknown. We investigated whether an EPA-enriched high-fat meal could improve postprandial vascular function. Seventeen healthy men ingested 2 test meals
Hyeon Ho Kim et al.
Journal of lipid research, 47(5), 921-930 (2006-02-10)
Skin aging can be attributed to photoaging (extrinsic) and chronological (intrinsic) aging. Photoaging and intrinsic aging are induced by damage to human skin attributable to repeated exposure to ultraviolet (UV) irradiation and to the passage of time, respectively. In our
Cindy A Francois et al.
The American journal of clinical nutrition, 77(1), 226-233 (2002-12-25)
Flaxseed oil is a rich source of 18:3n-3 (alpha-linolenic acid, or ALA), which is ultimately converted to 22:6n-3 (docosahexaenoic acid, or DHA), a fatty acid important for the development of the infant brain and retina. The objective of this study
R Luostarinen et al.
Prostaglandins, leukotrienes, and essential fatty acids, 55(3), 167-172 (1996-09-01)
12 volunteers with slightly elevated serum triglyceride levels were given 30 ml fish oil (5.4 g eicosapentaenoic acid and 3.2 g docosahexaenoic acid) daily for 4 weeks. The percentage of eicosapentaenoic acid increased (P < 0.01) and the percentage of
S Sipka et al.
Clinical immunology and immunopathology, 79(3), 224-228 (1996-06-01)
Free eicosapentaenoic acid (EPA) was found to inhibit dose dependently the chemiluminescence of human neutrophil granulocytes phagocytosing zymosan and their chemotaxis induced by C5a-containing zymosan-activated serum (ZAS) and platelet-activating factor. Rigidification of plasma membranes in the ZAS-treated cells could be
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