biological source
human lung
Quality Level
form
lyophilized powder
impurities
salt, free
solubility
H2O: >10 mg/mL (more soluble at pH>7)
UniProt accession no.
storage temp.
2-8°C
InChI
1S/C27H48N6O6/c1-9-17(6)23(32-24(36)19(13-15(2)3)30-18(7)34)26(38)29-14-21(35)31-22(16(4)5)27(39)33-12-10-11-20(33)25(37)28-8/h15-17,19-20,22-23H,9-14H2,1-8H3,(H,28,37)(H,29,38)(H,30,34)(H,31,35)(H,32,36)/t17-,19-,20-,22-,23-/m0/s1
InChI key
DPUYCSDGMSDKKV-MKBYFEBXSA-N
Gene Information
human ... ELN(2006)
Application
Elastin is a structural protein which has been used in studies of chronic obstructive pulmonary disease (COPD). It may be used to investigate why there is a lack of repair for these proteins in patients with COPD.
Preparation Note
Prepared from E7152 using the method of Partrige, et al.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
高风险级别生物产品--人源产品
此项目有
The chemistry of connective tissues. 2. Soluble proteins derived from partial hydrolysis of elastin.
S M PARTRIDGE et al.
The Biochemical journal, 61(1), 11-21 (1955-09-01)
Wei Li et al.
Arteriosclerosis, thrombosis, and vascular biology, 33(5), 1028-1035 (2013-03-16)
Patients with elastin deficiency attributable to gene mutation (supravalvular aortic stenosis) or chromosomal microdeletion (Williams syndrome) are characterized by obstructive arteriopathy resulting from excessive smooth muscle cell (SMC) proliferation, mural expansion, and inadequate vessel size. We investigated whether rapamycin, an
Ju-Yi Chen et al.
Arteriosclerosis, thrombosis, and vascular biology, 33(4), 839-846 (2013-02-16)
One potential mechanism through which obesity exerts adverse effects on the vascular system is by increasing aortic stiffness, a change known to be predictive of increased cardiovascular mortality. The aim of this study was to investigate the pathophysiology that links
Chris A Bashur et al.
Stem cells translational medicine, 2(6), 401-408 (2013-05-17)
Abdominal aortic aneurysms (AAAs) are potentially fatal conditions that are characterized by decreased flexibility of the aortic wall due to proteolytic loss of the structural matrix. This leads to their gradual weakening and ultimate rupture. Drug-based inhibition of proteolytic enzymes
Andrew L Wishart et al.
Science advances, 6(43) (2020-10-23)
The extracellular matrix (ECM), a major component of the tumor microenvironment, promotes local invasion to drive metastasis. Here, we describe a method to study whole-tissue ECM effects from disease states associated with metastasis on tumor cell phenotypes and identify the
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| E7277-2MG | 04061833261552 |
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