E7278
Anti-S1P2, C-Terminal antibody produced in rabbit
~1 mg/mL, fractionated antiserum, buffered aqueous solution
别名:
Anti-EDG-5, Anti-Endothelial Cell Differentiation Gene 5
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关于此项目
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
3
biological source
rabbit
Quality Segment
conjugate
unconjugated
antibody form
fractionated antiserum
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen ~42 kDa by SDS-PAGE
species reactivity
human
concentration
~1 mg/mL
technique(s)
western blot: suitable
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... S1PR2(9294)
Immunogen
synthetic peptide (approximately 2.5 kDa, native) derived from the C-terminal region of the EDG-5/S1P2 receptor.
Application
Anti-S1P2, C-Terminal antibody produced in rabbit is suitable for western blotting.
Biochem/physiol Actions
Sphingosine-1-phosphate receptor 2 (S1PR2 or S1P2) is a human gene encodeing a G protein-coupled receptor. It binds the lipid signaling molecule sphingosine 1-phosphate (S1P) and regulates vascular permeability along with S1P1. Activation of S1P2R in endothelial cells increases vascular permeability. It is a bioactive lysophospholipid capable of inducing a wide spectrum of biological responses. S1P acts as an intercellular mediator by interacting with the endothelial differentiation gene (EDG)/S1P family of G protein-coupled receptors. S1P2 receptor is involved in S1P-induced platelet aggregation and Rho kinase activation. Type 2 diabetes patient responds to S1P.
Physical form
Supplied in phosphate buffered saline, pH 7.3, containing 0.08% sodium azide.
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存储类别
10 - Combustible liquids