E7887
17α-Ethynylestradiol 3-cyclopentyl ether
别名:
17α-Ethynyl-1,3,5(10)-estratriene-3,17β-diol 3-cyclopentyl ether, Quinestrol
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关于此项目
经验公式（希尔记法）:
C25H32O2
化学文摘社编号:
分子量:
364.52
EC 号:
MDL编号:
UNSPSC代码:
12352202
PubChem化学物质编号:
NACRES:
NA.77
表单
solid
质量水平
运输
ambient
储存温度
room temp
SMILES字符串
[H][C@]12CC[C@@]3(C)[C@@]([H])(CC[C@@]3(O)C#C)[C@]1([H])CCc4cc(OC5CCCC5)ccc24
InChI
1S/C25H32O2/c1-3-25(26)15-13-23-22-10-8-17-16-19(27-18-6-4-5-7-18)9-11-20(17)21(22)12-14-24(23,25)2/h1,9,11,16,18,21-23,26H,4-8,10,12-15H2,2H3/t21-,22-,23+,24+,25+/m1/s1
InChI key
PWZUUYSISTUNDW-VAFBSOEGSA-N
基因信息
human ... ESR1(2099), ESR2(2100)
警示用语：
Danger
危险分类
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 1B - Repr. 1B
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
新产品
此项目有
Tao Tang et al.
Chemosphere, 89(11), 1419-1425 (2012-07-10)
Quinestrol is synthetic estrogen used in contraceptive and hormone replacement therapy and occasionally for treating breast cancer and prostate cancer. It can make its way into the environment through sewage discharge and waste disposal produced by human excretions. In this
Xiao-Hui Lv et al.
Experimental animals, 60(5), 489-496 (2011-11-02)
The contraceptive effects of quinestrol in Mongolian gerbils were examined. The results showed that body weight significantly increased after quinestrol treatment, except in the group that received the highest dose. The gonadosomatic index of ovaries decreased, whereas that of uteri
Wei Shen et al.
Experimental animals, 60(5), 445-453 (2011-11-02)
The hypothesis that quinestrol exerts testicular damage via oxidative stress was investigated in male gerbils using a daily oral gavage of 3.5 mg/kg body weight for 2 weeks (the multidose-treated group) or 35 mg/kg body weight (the single-dose-treated group). The
Xiaohui Lv et al.
Theriogenology, 77(6), 1223-1231 (2012-01-31)
Quinestrol, a synthetic estrogen with marked estrogenic effects and prolonged activity, has potential as a contraceptive for Mongolian gerbils. The objective of this study was to describe the effects of quinestrol on reproductive hormone expression, secretion, and receptor levels in
Xiaohui Lv et al.
Zoological science, 29(1), 37-42 (2012-01-12)
The effects of treatment with a combination of levonorgestrel and quinestrol (EP-1; ratio of 2:1) on reproductive hormone levels and the expression of their receptors in female Mongolian gerbils were examined. We show that serum follicle-stimulating hormone (FSH) and luteinizing
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