E7906
艾美拉唑镁抗溃疡病药 镁盐 水合物
≥98% (HPLC), proton pump inhibitor, powder
别名:
(S)-奥美拉唑镁, (T-4)-双[6-甲氧基-2-[(S)-[(4-甲氧基-3,5-二甲基-2-吡啶基)甲基]亚磺酰基-κO]-1H-苯并咪唑基-κN3]-镁 水合物, 埃索美拉唑镁三水合物
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关于此项目
经验公式(希尔记法):
C34H36MgN6O6S2 · xH2O
CAS Number:
分子量:
713.12 (anhydrous basis)
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
Product Name
艾美拉唑镁抗溃疡病药 镁盐 水合物, ≥98% (HPLC)
质量水平
方案
≥98% (HPLC)
表单
powder
旋光性
[α]/D -128 to -146°, c = 0.5 in methanol
颜色
white to off-white
溶解性
DMSO: ≥5 mg/mL
创始人
AstraZeneca
储存温度
2-8°C
SMILES字符串
O.COc1ccc2n([Mg]n3c(nc4cc(OC)ccc34)S(=O)Cc5ncc(C)c(OC)c5C)c(nc2c1)S(=O)Cc6ncc(C)c(OC)c6C
InChI
1S/2C17H18N3O3S.Mg.H2O/c2*1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17;;/h2*5-8H,9H2,1-4H3;;1H2/q2*-1;+2;/t2*24-;;/m00../s1
InChI key
LGRFYKXKCZKDLS-DIYDTZFBSA-N
相关类别
警示用语:
Warning
危险声明
危险分类
Acute Tox. 4 Oral
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Mark Rochman et al.
The Journal of allergy and clinical immunology, 147(5), 1924-1935 (2020-12-09)
Proton pump inhibitors (PPIs) have been recognized as a primary treatment of eosinophilic esophagitis (EoE), an allergic inflammatory disease of the esophageal mucosa. The mechanisms underlying esophageal epithelial responses to PPIs remain poorly understood. We hypothesized that PPIs can counteract
Esomeprazole increases airway surface liquid pH in primary Cystic Fibrosis epithelial cells
Delpiano L, et al.
Frontiers in Pharmacology, 9 (2018)
Yukiko Nakagawa et al.
Biological & pharmaceutical bulletin, 43(4), 682-687 (2020-04-03)
We previously showed that adhesive aggregates were formed when levofloxacin hydrate tablets and lansoprazole orally disintegrating (OD) tablets were suspended in water in the clinical context. In this study, we have clarified the factors causing aggregate formation, focusing on the
Esomeprazole
Scott LJ, et al.
Drugs, 62(10), 1503-1538 (2002)
A review of esomeprazole in the treatment of gastroesophageal reflux disease (GERD)
Kalaitzakis E and Bjornsson E
Therapeutics and Clinical Risk Management, 3(4), 653-653 (2007)
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