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关于此项目
经验公式(希尔记法):
C16H26NClO4
化学文摘社编号:
分子量:
331.83
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
solid
Storage condition:
desiccated
产品名称
Esmolol 盐酸盐, ≥98% (HPLC), solid
Quality Segment
assay
≥98% (HPLC)
form
solid
storage condition
desiccated
mp
89.0-90.6 °C
solubility
H2O: 12 mg/mL
originator
Baxter
storage temp.
2-8°C
SMILES string
Cl.COC(=O)CCc1ccc(OCC(O)CNC(C)C)cc1
InChI
1S/C16H25NO4.ClH/c1-12(2)17-10-14(18)11-21-15-7-4-13(5-8-15)6-9-16(19)20-3;/h4-5,7-8,12,14,17-18H,6,9-11H2,1-3H3;1H
InChI key
GEKNCWBANDDJJL-UHFFFAOYSA-N
Gene Information
human ... ADRB1(153), ADRB2(154)
Application
Esmolol hydrochloride (ESM) may be used as a standard in spectrophotometric and electrochemical method for the determination of ESM in biological samples and pharmaceutical formulations.
Biochem/physiol Actions
Esmolol hydrochloride (ESM) is a class II antiarrhythmic drug. It is used to decrease the force and rate of heart contractions during surgery. Overdose of ESM can lead to side effects such as bradycardia, cardiac arrest, hypoventilation, mood disorder, and coma.
Esmolol hydrochloride is a ultrashort-acting β1 adrenoceptor antagonist (β1 receptor occupancy = 84.7%).
Features and Benefits
This compound is featured on the β-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Baxter. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves