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Merck
CN

E8031

Esmolol 盐酸盐

≥98% (HPLC), β1 adrenoceptor antagonist , solid

别名:

4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzenepropanoic acid methyl ester hydrochloride 盐酸盐

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关于此项目

经验公式(希尔记法):
C16H26NClO4
化学文摘社编号:
分子量:
331.83
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
solid
Storage condition:
desiccated
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产品名称

Esmolol 盐酸盐, ≥98% (HPLC), solid

Quality Segment

assay

≥98% (HPLC)

form

solid

storage condition

desiccated

mp

89.0-90.6 °C

solubility

H2O: 12 mg/mL

originator

Baxter

storage temp.

2-8°C

SMILES string

Cl.COC(=O)CCc1ccc(OCC(O)CNC(C)C)cc1

InChI

1S/C16H25NO4.ClH/c1-12(2)17-10-14(18)11-21-15-7-4-13(5-8-15)6-9-16(19)20-3;/h4-5,7-8,12,14,17-18H,6,9-11H2,1-3H3;1H

InChI key

GEKNCWBANDDJJL-UHFFFAOYSA-N

Gene Information

Application

Esmolol hydrochloride (ESM) may be used as a standard in spectrophotometric and electrochemical method for the determination of ESM in biological samples and pharmaceutical formulations.

Biochem/physiol Actions

Esmolol hydrochloride (ESM) is a class II antiarrhythmic drug. It is used to decrease the force and rate of heart contractions during surgery. Overdose of ESM can lead to side effects such as bradycardia, cardiac arrest, hypoventilation, mood disorder, and coma.
Esmolol hydrochloride is a ultrashort-acting β1 adrenoceptor antagonist (β1 receptor occupancy = 84.7%).

Features and Benefits

This compound is featured on the β-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Baxter. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.


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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves



历史批次信息供参考:

分析证书(COA)

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