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Merck
CN

E8512

Sigma-Aldrich

Ethylmorphine

别名:

Morphine 3-ethyl ether

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关于此项目

经验公式（希尔记法）:
C19H23NO3
化学文摘社编号:
76-58-4
分子量:
313.39
EC 号:
200-970-7
MDL编号:
MFCD00083327
UNSPSC代码:
12352200
PubChem化学物质编号:
24894676
NACRES:
NA.77

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药品控制

USDEA Schedule II; Home Office Schedule 2; stupéfiant (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal); Kábítószer / Narcotic Drug (Hungary), 78/2022. (XII. 28.) BM rendelet

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

forensics and toxicology
veterinary

储存温度

2-8°C

SMILES字符串

CCOc1ccc2C[C@@H]3C4C=C[C@H](O)[C@@H]5Oc1c2[C@]45CCN3C

InChI

1S/C19H23NO3/c1-3-22-15-7-4-11-10-13-12-5-6-14(21)18-19(12,8-9-20(13)2)16(11)17(15)23-18/h4-7,12-14,18,21H,3,8-10H2,1-2H3/t12-,13+,14-,18-,19-/m0/s1

InChI key

OGDVEMNWJVYAJL-LEPYJNQMSA-N

生化/生理作用

Narcotic analgesic; antitussive

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H302,H336

预防措施声明

P301 + P312 + P330

危险分类

Acute Tox. 4 Oral - STOT SE 3

靶器官

Central nervous system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

法规信息

新产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
049K4008
107K4116
077K4072
037K4074
037K4011

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Aliaa Nabil ElMeshad et al.
AAPS PharmSciTech, 21(7), 244-244 (2020-08-29)
Ethylmorphine hydrochloride (EtM) is a derivative of morphine used as analgesic to treat severe pain in case of cancer and bone injury. This study aimed to formulate and evaluate core in cup tablets containing 2 doses of EtM, the cup
Virginia Tzankova et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 92, 569-579 (2017-06-04)
The toxic liver impairment caused by free radical injury or excessive reactive oxigen species (ROS) formation could be effectivelly attenuated by natural antioxidants. The present study aimed to explore and compare the hepatoprotective and antioxidant effects of free and encapsulated
G Virkel et al.
Journal of veterinary pharmacology and therapeutics, 33(3), 295-303 (2010-06-19)
The intestinal mucosa plays a capital role in dictating the bioavailability of a large array of orally ingested drugs and toxicants. The activity and the expression of several xenobiotic metabolizing enzymes were measured in subcellular fractions from the duodenal mucosa
W A Daniel et al.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 15(1), 103-110 (2004-12-02)
The aim of the present study was to investigate the influence of classic and atypical neuroleptics on the activity of rat CYP2D measured as a rate of ethylmorphine O-deethylation. The reaction was studied in control liver microsomes in the presence
Elisabeth Leere Oiestad et al.
Journal of analytical toxicology, 35(5), 280-293 (2011-05-31)
An ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS-MS) method for screening of drugs in whole blood has been developed and validated. Samples were prepared by supported liquid-liquid extraction on ChemElute(®) columns with ethyl acetate/heptane (4:1). LC separation was achieved with an
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