E9502
EPPS
≥99.5% (titration)
别名:
4-(2-羟乙基)-1-哌嗪丙磺酸, 4-羟乙基哌嗪丙磺酸, N-(2-羟乙基)哌嗪-N′-(3-丙磺酸), HEPPS
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关于此项目
经验公式(希尔记法):
C9H20N2O4S
CAS Number:
分子量:
252.33
Beilstein:
3957385
EC 号:
MDL编号:
UNSPSC代码:
12161700
PubChem化学物质编号:
NACRES:
NA.25
质量水平
方案
≥99.5% (titration)
表单
powder
pH值(酸碱度)
7.3-8.7
有效pH范围
7.3-8.7
pKa (25 °C)
8.0
pKa
8
mp
237-239 °C (lit.)
溶解性
H2O: 25 g + 50 mL, clear, colorless
λmax
A290 at ≤0.1 (C=33% w/w)
应用
diagnostic assay manufacturing
SMILES字符串
OCCN1CCN(CCCS(O)(=O)=O)CC1
InChI
1S/C9H20N2O4S/c12-8-7-11-5-3-10(4-6-11)2-1-9-16(13,14)15/h12H,1-9H2,(H,13,14,15)
InChI key
OWXMKDGYPWMGEB-UHFFFAOYSA-N
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应用
EPPS 已用于:
- 验证 pH 变化对中肠后部(PMG)内容物和中肠前部(AMG)组织匀浆蛋白水解活性的影响
- 制备染色脱色液以去除染色强烈的凝胶片
- 制备用于凝胶内酶解的消化缓冲液
- 重悬酶解后的肽,用于处理脑源性细胞外囊泡(EV)蛋白和 16 倍同量异序串联质量标签(TMT)肽标记
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Bernhard Sissolak et al.
Journal of industrial microbiology & biotechnology, 46(8), 1167-1178 (2019-06-09)
Recombinant monoclonal antibodies are predominantly produced in mammalian cell culture bioprocesses. Post-translational modifications affect the micro-heterogeneity of the product and thereby influence important quality attributes, such as stability, solubility, pharmacodynamics and pharmacokinetics. The analysis of the surface charge distribution of
YoungSoo Kim et al.
Science advances, 5(4), eaav1388-eaav1388 (2019-04-20)
Detection of amyloid-β (Aβ) aggregates contributes to the diagnosis of Alzheimer disease (AD). Plasma Aβ is deemed a less invasive and more accessible hallmark of AD, as Aβ can penetrate blood-brain barriers. However, correlations between biofluidic Aβ concentrations and AD
Amir Ata Saei et al.
Nature communications, 10(1), 5715-5715 (2019-12-18)
Deconvolution of targets and action mechanisms of anticancer compounds is fundamental in drug development. Here, we report on ProTargetMiner as a publicly available expandable proteome signature library of anticancer molecules in cancer cell lines. Based on 287 A549 adenocarcinoma proteomes
Yang You et al.
Journal of extracellular vesicles, 11(1), e12183-e12183 (2022-01-15)
In neurodegenerative diseases, extracellular vesicles (EVs) transfer pathogenic molecules and are consequently involved in disease progression. We have investigated the proteomic profiles of EVs that were isolated from four different human-induced pluripotent stem cell-derived neural cell types (excitatory neurons, astrocytes
Heeseon An et al.
Molecular cell, 74(5), 891-908 (2019-04-23)
Cells respond to nutrient stress by trafficking cytosolic contents to lysosomes for degradation via macroautophagy. The endoplasmic reticulum (ER) serves as an initiation site for autophagosomes and is also remodeled in response to nutrient stress through ER-phagy, a form of
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