E9658
依那普利 二水合物
≥98% (HPLC)
别名:
(2S)-1-[(2S)-2-[[(1S)-1-Carboxy-3-phenyl-propyl]amino]propanoyl]pyrrolidine-2-carboxylic acid, Vasotec
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关于此项目
经验公式（希尔记法）:
C18H24N2O5 ·2H2O
化学文摘社编号:
分子量:
384.42
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
278-459-3
MDL number:
Assay:
≥98% (HPLC)
Quality Segment
assay
≥98% (HPLC)
solubility
H2O: 14 mg/mL at 60 °C (warming for 5 minutes), DMSO: 64 mg/mL
originator
Merck & Co., Inc., Kenilworth, NJ, U.S.
storage temp.
room temp
SMILES string
O.O.C[C@H](N[C@@H](CCc1ccccc1)C(O)=O)C(=O)N2CCC[C@H]2C(O)=O
InChI
1S/C18H24N2O5.2H2O/c1-12(16(21)20-11-5-8-15(20)18(24)25)19-14(17(22)23)10-9-13-6-3-2-4-7-13;;/h2-4,6-7,12,14-15,19H,5,8-11H2,1H3,(H,22,23)(H,24,25);2*1H2/t12-,14-,15-;;/m0../s1
InChI key
MZYVOFLIPYDBGD-MLZQUWKJSA-N
Gene Information
human ... ACE(1636)
Biochem/physiol Actions
Enalapril, the ethyl ester of enalaprilat exhibits slight pharmacological activity until it is hydrolyzed in the liver to enalaprilat. Enalaprilat, a IV form of an angiotensin-converting-enzyme inhibitor (ACE) prevents the transformation of angiotensin I to angiotensin II, a potent vasoconstrictor.
Enalaprilat is an inhibitor of angiotensin converting enzyme (ACE), antihypertensive, and a Bradykinin B1 receptor activator.
Enalaprilat is an inhibitor of angiotensin converting enzyme (ACE), antihypertensive, and a Bradykinin B1 receptor activator. Enalaprilat has nM potency versus ACE and also activates B1 receptors to release NO.
Features and Benefits
This compound is featured on the Angiotensin Receptors and Bradykinin Receptors pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Merck & Co., Inc., Kenilworth, NJ, U.S.. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
商品
We offer many products related to angiotensin receptors for your research needs.
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| E9658-5MG | 04061833609156 |
| E9658-25MG | 04061833609149 |