产品名称
MISSION® esiRNA, targeting human RPGRIP1L
description
Powered by Eupheria Biotech
product line
MISSION®
form
lyophilized powder
esiRNA cDNA target sequence
TTCCTCCAGCATCCTCTGTTAGCACACTAGTTTTAGCACCAAGACCTAAACCAAGACAACGTTTAACACCTGTAGATAAGAAGGTATCTTTCGTGGATATCATGCCACATCAGAGTGATGTTTCACAAGAAGGCAGTGTAGATGAGGTAAAAGAGAATACTGAGAAAATGCAGCAAGGAAAAGATGATGTGTCTTTACTATCTGAAGGTCAGCTTGCAGAACAAAGCTTGGCATCTTCTGAAGATGAAACAGAAATAACAGAGGACTTGGAACCAGAAGTTGAAGAGGACATGTCAGCTTCTGACAGTGATGACTGTATTATTCCAGGTCCTATCTCCAAGAATATCAAACAGCCATCAGAAAAAATTCGGATTGAGATCATAGCTCTAAGCCTTAATGATTCTCAAGTAACCATGGATGACACTATCCAACGGC
Ensembl | human accession no.
NCBI accession no.
shipped in
ambient
storage temp.
−20°C
Quality Level
Gene Information
human ... RPGRIP1L(23322), RPGRIP1L(23322)
General description
MISSION® shRNA是核糖核酸内切酶制备的siRNA。它们是靶向相同mRNA序列的siRNA异质混合物。这些多重沉默触发（multiple silencing trigger）导致高度特异性的、有效的基因沉默。
如需其他详细信息并查看所有可用的esiRNA选项，请访问SigmaAldrich.com/esiRNA。
如需其他详细信息并查看所有可用的esiRNA选项，请访问SigmaAldrich.com/esiRNA。
Legal Information
MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Yeon Ja Choi et al.
PLoS genetics, 15(1), e1007914-e1007914 (2019-01-29)
Cilia-related proteins are believed to be involved in a broad range of cellular processes. Retinitis pigmentosa GTPase regulator interacting protein 1-like (RPGRIP1L) is a ciliary protein required for ciliogenesis in many cell types, including epidermal keratinocytes. Here we report that
Jayne F Martin Carli et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 32(7), 3946-3956 (2018-02-22)
Genetic variants within the FTO (α-ketoglutarate-dependent dioxygenase) gene have been strongly associated with a modest increase in adiposity as a result of increased food intake. These risk alleles are associated with decreased expression of both FTO and neighboring RPGRIP1L (retinitis
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