description
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product line
MISSION®
form
lyophilized powder
esiRNA cDNA target sequence
CACAGGGCTAAAGCCTGAACAGGTGGAGCGGCTGATCAAGGAGTTCTCCATCTACATGACAAAAGATGGCCGCATCTCTGTGGCAGGGGTCACCTCCAGCAACGTGGGCTACCTTGCCCATGCCATTCACCAGGTCACCAAGTAATGTCCCTGGTGCGAGGAAACAGAGACAACCTTTCTGTCTTCAGCCTCTGCTATTGAGAGCTTCACACAGACAATGAGAGAGGGTGGATGGTGGTGAGTGGATCATTTCTTTCAGCCACAGTGTGTAACACTCAGCATTTGAATGTTTCTCAGAAAAGAACATGTAGTGACACAGGGCAGAGGCATCCATGGCTGGCGTCTGGAATATTAAACCAAACTCTCCCCGGTCCTTTTTTCTCCAACTTTTCTCAAAGAGTTTACATGTGCAAGAAAGTCATCGCACCAAAAAACCTGTCAATTATGCCATTGCAATATTTCAGAAGCTTTAACTGAAGTGTCAGGTTCCTCGTGAGAAACAGCACACGTT
Ensembl | human accession no.
NCBI accession no.
shipped in
ambient
storage temp.
−20°C
Quality Level
General description
MISSION® shRNA是核糖核酸内切酶制备的siRNA。它们是靶向相同mRNA序列的siRNA异质混合物。这些多重沉默触发（multiple silencing trigger）导致高度特异性的、有效的基因沉默。
如需其他详细信息并查看所有可用的esiRNA选项，请访问SigmaAldrich.com/esiRNA。
如需其他详细信息并查看所有可用的esiRNA选项，请访问SigmaAldrich.com/esiRNA。
Legal Information
MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
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Nick van Gastel et al.
Cell metabolism, 32(3), 391-403 (2020-08-09)
Cancer relapse begins when malignant cells pass through the extreme metabolic bottleneck of stress from chemotherapy and the byproducts of the massive cell death in the surrounding region. In acute myeloid leukemia, complete remissions are common, but few are cured.
Mylène Tajan et al.
Cell metabolism, 28(5), 721-736 (2018-08-21)
Numerous mechanisms to support cells under conditions of transient nutrient starvation have been described. Several functions of the tumor-suppressor protein p53 can contribute to the adaptation of cells to metabolic stress and help cancer cell survival under nutrient-limiting conditions. We
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