产品名称
MISSION® esiRNA, targeting human MAML3
description
Powered by Eupheria Biotech
product line
MISSION®
form
lyophilized powder
esiRNA cDNA target sequence
CCCTTATAGCACCACGCCTACCAGCCAACCAGGAATGTACAATATGAGCACAGGCATGACCCAAATGTTGCAGCATCCAAACCAAAGTGGCATGAGCATCACACATAACCAAGCCCAGGGACCGAGGCAACCTGCCTCTGGGCAGGGGGTTGGAATGGTGAGTGGCTTTGGTCAGAGCATGCTGGTGAACTCAGCCATTACCCAGCAACATCCACAGATGAAAGGGCCAGTAGGCCAGGCCTTGCCTAGGCCCCAAGCCCCTCCAAGGCTGCAGAGCCTTATGGGAACAGTCCAGCAAGGAGCACAAAGCTGGCAACAGAGGAGCTTGCAGGGCATGCCTGGGAGGACTAGTGGAGAATTGGGACCATTCAACAATGGCGCCAGCTACCCTCTTCAAGCTGGGCAGCCGAGACTGACCAAGCAGCACTTCCCACAGGGACTGAGCCAGTCAGTCGTGGATGCTA
Ensembl | human accession no.
shipped in
ambient
storage temp.
−20°C
Quality Level
Gene Information
human ... MAML3(55534), MAML3(55534)
General description
MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
Legal Information
MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
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Hideya Onishi et al.
Cellular immunology, 310, 199-204 (2016-08-16)
We investigated whether hypoxia-induced activation of Hh signaling contributes to PDL-1 expression in cancer and whether it affects the anti-tumor function of activated lymphocytes. Hypoxia augmented PDL-1 expression and inhibition of Hh signaling reduced PDL-1 expression under hypoxia. When activated
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