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Merck
CN

EHU049221

MISSION® esiRNA

targeting human CDCP1

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NACRES:
NA.51
UNSPSC Code:
41105324

主要文件

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产品名称

MISSION® esiRNA, targeting human CDCP1

description

Powered by Eupheria Biotech

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

CCCAACAATGGGGATGTAAGCAGCAAGGACACAGACATTCCCTTACTGAACACTCAGGAGCCCATGGAGCCAGCAGAATAACTTGATCCATTCCAGACGCTTTGCTGAGTTTCATAAAGCAGGGCACTGAGACACCCGTCCGTGTTCCTAACCAGAAATCCTAAAGAAGAGGAATTATACAGAAGGAACAGCAGGAGGTTTTCCTGGACACCGCCAACTTCACATTGCTCAGTGGACTCATTCTAAGGGCAAGACATTGAAAATGATGAATTCCAATCTGGATACAGTCATGACAGCTCATGTGCTCCTCAACTTAGGCTGTGCGGTTAGCCAGCCTGTAATGAGAGGAGAGAGGCCTGAGTCACCTAGCATAGGGTTGCAGCAAGCCCTGGATTCAGAGTG

Ensembl | human accession no.

ENSG00000163814

NCBI accession no.

NM_022842

shipped in

ambient

storage temp.

−20°C

Quality Level

100

Gene Information

human ... CDCP1(64866), CDCP1(64866)

相关类别

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

存储类别

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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QCS

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Lijun Huang et al.
Cancer management and research, 12, 3759-3769 (2020-06-18)
Emerging evidence have revealed significant contributions of CUB domain-containing protein-1 (CDCP1) in tumorigenesis, including colon, renal, ovarian, pancreatic, prostate and breast cancers. However, the roles of CDCP1 in cervical cancer (CC) still remain elusive. Quantitative reverse transcription polymerase chain reaction
Nina Noskovičová et al.
American journal of physiology. Lung cellular and molecular physiology, 314(5), L695-L707 (2018-01-20)
Fibroblasts are thought to be the prime cell type for producing and secreting extracellular matrix (ECM) proteins in the connective tissue. The profibrotic cytokine transforming growth factor-β1 (TGF-β1) activates and transdifferentiates fibroblasts into α-smooth muscle actin (α-SMA)-expressing myofibroblasts, which exhibit

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