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Merck
CN

EHU051631

MISSION® esiRNA

targeting human MEGF10

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NACRES:
NA.51
UNSPSC Code:
41105324

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产品名称

MISSION® esiRNA, targeting human MEGF10

description

Powered by Eupheria Biotech

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

TGTCAAAACGGAGCTGACTGCGACCACATTTCTGGGCAGTGTACTTGCCGCACTGGATTCATGGGACGGCACTGTGAGCAGAAGTGCCCTTCAGGAACATATGGCTATGGCTGTCGCCAGATATGTGATTGTCTGAACAACTCCACCTGCGACCACATCACTGGGACCTGTTACTGCAGCCCCGGATGGAAGGGAGCGAGATGTGATCAAGCTGGTGTTATCATAGTTGGAAATCTGAACAGCTTAAGCCGAACCAGTACTGCTCTCCCTGCTGATTCCTACCAGATCGGGGCCATTGCAGGCATCATCATTCTTGTCCTAGTTGTTCTCTTCCTACTGGCATTGTTCATTATTTATAGACACAAGCAGAAGGGAAAGGAATCAAGCATGCCAGCAGTTAC

Ensembl | human accession no.

ENSG00000145794

NCBI accession no.

NM_032446

shipped in

ambient

storage temp.

−20°C

Quality Level

100

Gene Information

human ... MEGF10(84466), MEGF10(84466)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

存储类别

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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Jessica Charlet et al.
Molecular carcinogenesis, 56(4), 1290-1301 (2016-11-20)
Neuroblastoma is a childhood cancer in which many children still have poor outcomes, emphasising the need to better understand its pathogenesis. Despite recent genome-wide mutation analyses, many primary neuroblastomas do not contain recognizable driver mutations, implicating alternate molecular pathologies such
Madhurima Saha et al.
Human molecular genetics, 28(14), 2365-2377 (2019-07-04)
MEGF10 myopathy is a rare inherited muscle disease that is named after the causative gene, MEGF10. The classic phenotype, early onset myopathy, areflexia, respiratory distress and dysphagia, is severe and immediately life-threatening. There are no disease-modifying therapies. We performed a

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