产品名称
MISSION® esiRNA, targeting human ADAMTS3
description
Powered by Eupheria Biotech
product line
MISSION®
form
lyophilized powder
esiRNA cDNA target sequence
TGAACCATGTTTGGGAGACAAGTCCATATTCTGTCAAATGGAAGTGTTGGCACGATACTGCTCCATACCAGGTTATAACAAGTTATGTTGTGAGTCCTGCAGCAAGCGCAGTAGCACCCTGCCACCACCATACCTTCTAGAAGCTGCTGAAACTCATGATGATGTCATCTCTAACCCTAGTGACCTCCCTAGATCTCTAGTGATGCCTACATCTTTGGTTCCTTATCATTCAGAGACCCCTGCAAAGAAGATGTCTTTGAGTAGCATCTCTTCAGTGGGAGGTCCAAATGCATATGCTGCTTTCAGGCCAAACAGTAAACCTGATGGTGCTAATTTACGCCAGAGGAGTGCTCAGCAAGCAGGAAGTAAGACTGTGAGACTGGTCACCGTACCATCCTCCCCACCCACCAAGAGGGTCCACCTCAGTTCAGCTTCACAAATGGCTG
Ensembl | human accession no.
NCBI accession no.
shipped in
ambient
storage temp.
−20°C
Quality Level
Gene Information
human ... ADAMTS3(9508), ADAMTS3(9508)
General description
MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
Legal Information
MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Pingping Ren et al.
Scientific reports, 7(1), 12351-12351 (2017-09-29)
Sporadic aortic aneurysm and dissections (AADs) are common vascular diseases that carry a high mortality rate. ADAMTS-4 (a disintegrin-like and metalloproteinase with thrombospondin motifs-4) is a secreted proteinase involved in inflammation and matrix degradation. We previously showed ADAMTS-4 levels were
Zheng Li et al.
PloS one, 9(10), e109595-e109595 (2014-10-10)
The mechanistic basis of obesity-associated intervertebral disc degeneration (IDD) is unclear. Aberrant expression of aggrecan and its degrading enzymes ADAMTS-4 and ADAMTS-5 is implicated in the development of IDD. Here, we investigated the effect of leptin, a hormone with increased
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