产品名称
MISSION® esiRNA, targeting human DVL1
description
Powered by Eupheria Biotech
product line
MISSION®
form
lyophilized powder
esiRNA cDNA target sequence
CCCTGTCTGGAGTAGGGATCTAATTTATTTATTTATTGCCTGGCCGGTGACTCGGGGGAGGAGGCGACCCTGTCATCTGTCCCACCTGCTGCTGCCCCTTGGAGCAGCCTGCACCTTCTCTCCTCCCATCCGGCAACAGTCTGAAAGTACGTGGAGGACGGGACCGGAAGACGAGAGAGGGCTGGACATCCTGCCCACCGTGTCCCAGCCAGGGCAGGGAGGGACCATGGCCCGCAGGGTCAAGGGGCCCCGATGTGCACAGCTGCCACAGGGAGGGAGGTCTTGGGGAGATGGGCAGTCAGGTGGCCCGTCCTTGGTGAGTGCACACACTGCGCGCACACATCGCGGCCTTCCTGGCTTCTCTGGCCCCCACGTGTCTGTGCTGTAGATACTGTATCAAAGTCCCAGCGTTTAGATGG
Ensembl | human accession no.
NCBI accession no.
shipped in
ambient
storage temp.
−20°C
Quality Level
Gene Information
human ... DVL1(1855), DVL1(1855)
General description
MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
Legal Information
MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Ceyda Çalışkan et al.
Molecular biology reports, 44(5), 391-397 (2017-08-26)
Dishevelled (Dvl) proteins are activated by Wnt pathway stimulation and have crucial roles in the regulation of β-catenin destruction complex. CYLD is a tumor suppressor and a deubiquitination enzyme. CYLD negatively regulates the Wnt/β-catenin signaling pathway by deubiquitinating Dvl proteins.
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