description
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product line
MISSION®
form
lyophilized powder
esiRNA cDNA target sequence
TGATGATCATGAAATGCGAAATGAAGTTTATCATAGGAAAATCATCTCTTGGTTTGGTGATTCCCCCTTGGCTCTTTTTGGCTTACATCAACTAATAGAATATGGAAAGAAGTCTGGGAAAAAAGCAGGAGATTGGTATGGACCAGCTGTGGTTGCTCACATTTTAAGAAAAGCAGTTGAAGAAGCAAGGCATCCTGATTTACAAGGAATAACTATTTATGTTGCACAAGATTGTACAGTTTACAATTCTGATGTAATTGATAAACAGAGTGCTTCCATGACTTCTGATAATGCAGATGACAAAGCTGTTATTATTCTAGTTCCTGTTAGACTTGGTGGAGAAAGAACCAACACCGACTACTTAGAATTTGTGAAGGGTATTTTAAGCCTGGAATATTGTGTGGGTATTATTGGTGGCA
Ensembl | human accession no.
NCBI accession no.
shipped in
ambient
storage temp.
−20°C
Quality Level
General description
MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
Legal Information
MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Martina Antonelli et al.
Oncotarget, 8(13), 21692-21709 (2017-04-21)
The efficacy of Ataxia-Telangiectasia Mutated (ATM) kinase signalling inhibition in cancer therapy is tempered by the identification of new emerging functions of ATM, which suggests that the role of this protein in cancer progression is complex. We recently demonstrated that
Alexander Agrotis et al.
Autophagy, 15(6), 976-997 (2019-01-22)
Macroautophagy/autophagy is a cellular degradation pathway that delivers cytoplasmic material to lysosomes via double-membrane organelles called autophagosomes. Lipidation of ubiquitin-like LC3/GABARAP proteins on the autophagosome membrane is important for autophagy. The cysteine protease ATG4 executes 2 LC3/GABARAP processing events: priming
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