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Merck
CN

EHU061241

MISSION® esiRNA

targeting human RASSF6

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NACRES:
NA.51
UNSPSC Code:
41105324
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description

Powered by Eupheria Biotech

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

TCTCTTGGAATCCATTCTTCAAAGATTAAATGAAGAAGAGAAAAGAGAGATTCAAAGAATAGTAACAAAATTCAATAAAGAAAAGGCGATTATACTGAAATGTCTTCAAAATAAACTAGTAATAAAAACAGAGACAACAGTTTAGCAGTACAAGCTTCTATTGCTAAAACATTTCAAAAAACTCAGAGATATTACTCTTTGATGAATGCATAAGTTCTGTACTTGCATTTATACGAACATATATGAGACTTGAATCGTAGAAAATTGAATGTCAAAAAAAGCTCATTTCTTTTTGAAGTGATGAGGTTAATTAGGGTTCACAGTTGGACAAAATGAGTTTGAGTTTAGTTTCAGTAACTGAAATAAGCTTGAATACTGCATATGCCAAATAGCTTTTATAGTAAACCATGTAATGAACTCAAATTTAAATGGTGTCTTCAGATAAGCAGTTTAAACTTCATTTAGCTTGGACTCTCAAGA

Ensembl | human accession no.

NCBI accession no.

shipped in

ambient

storage temp.

−20°C

Quality Level

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

存储类别

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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分析证书(COA)

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Hua Wang et al.
Journal of cellular physiology, 235(2), 1469-1479 (2019-07-06)
Aberrant loss of tumor-suppressor genes plays a crucial role in tumorigenesis and development of colorectal cancer (CRC). Extensive studies have reported tha hypermethylation of Ras association domain family member 6 (RASSF6) is common in various solid tumors. Another important mode
Rui Zhou et al.
Oncotarget, 8(33), 55162-55175 (2017-09-15)
Distant metastasis is the primary barrier for the successful treatment of patients with colorectal cancer, and thus, searching for new therapeutic targets by further exploring the molecular mechanisms of colorectal cancer metastasis is important. In this study, we investigated the

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