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Merck
CN

EHU061751

MISSION® esiRNA

targeting human NEO1

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关于此项目

NACRES:
NA.51
UNSPSC Code:
41105324
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description

Powered by Eupheria Biotech

Quality Level

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

TGGTGCATTCCAAACACAATAAACCTGATGAAGGTTATTATCAGTGTGTGGCCACTGTTGAGAGTCTTGGAACTATTATCAGTAGAACAGCGAAGCTCATAGTAGCAGGTCTTCCAAGATTTACCAGCCAACCAGAACCTTCCTCAGTTTATGCTGGGAACAATGCAATTCTGAATTGTGAAGTTAATGCAGATTTGGTCCCATTTGTGAGGTGGGAACAGAACAGACAACCCCTTCTTCTGGATGATAGAGTTATCAAACTTCCAAGTGGAATGCTGGTTATCAGCAATGCAACTGAAGGAGATGGCGGGCTTTATCGCTGCGTAGTGGAAAGTGGTGGGCCACCAAAGTATAGTGATGAAGTTGAATTGAAGGTTCTTCCAGATCCTGAGGTGATATCAGACTTGGTATTTTTGAAACAGCCTTCTCCCTTAGTCAGAGTCATTGGTCAGGATGTAGTGTTGCCATGTGTTGCTTC

Ensembl | human accession no.

NCBI accession no.

shipped in

ambient

storage temp.

−20°C

Gene Information

human ... NEO1(4756)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany


存储类别

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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Esma Lejmi et al.
Vascular cell, 6(1), 1-1 (2014-01-30)
Netrins are secreted molecules involved in axon guidance and angiogenesis. We previously showed that Netrin-4 acts as an anti-angiogenic factor by inhibiting endothelial cell (EC) functions. In this study, we investigated the effects of Netrin-4 on vascular smooth muscle cell
Vishal Chaturvedi et al.
Scientific reports, 9(1), 4110-4110 (2019-03-13)
Neogenin1 (NEO1) is a receptor of the Deleted in Colorectal Carcinoma (DCC)/Frazzled/UNC-40 family, which regulates axon guidance but can also stabilize epithelial adherens junctions. NEO1 and DCC are also tumor suppressors that can inhibit metastasis by acting as dependence receptors.
Mari Kitayama et al.
PloS one, 6(9), e25234-e25234 (2011-10-01)
By causing damage to neural networks, spinal cord injuries (SCI) often result in severe motor and sensory dysfunction. Functional recovery requires axonal regrowth and regeneration of neural network, processes that are quite limited in the adult central nervous system (CNS).



全球贸易项目编号

货号GTIN
EHU061751-50UG04061828328154
EHU061751-20UG04061828563739