description
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product line
MISSION®
form
lyophilized powder
esiRNA cDNA target sequence
GATGGTCCTGTCCATCTGCTTGTGCCGGCACGTCCATTCCGAAGACTACAGCAAGGTCCCCAAGTACTGAGGCAGCTGCTATCCCCATCTCCCTGCCTGGCCCCCAACCTCAGGGCTCCCAGGGGTCTCCCTGGCTCCCTCCTCCAGGCCTGCCTCCCACTTCACTGCGAAGACCCTCTTGCCCATCCTGACTGAAAGTAGGGGGCTTTCTGGGGCCTAGCGATCTCTCCTGGCCTATCCGCTGCCAGCCTTGAGCCCTGGCTGTTCTGTGGTTCCTCTGCTCACCGCCCATCAGGGTTCTCTTAGCAACTCAGAGAAAAATGCTCCCCACAGCGTCCCTGGCGCAGGTGGGCTGGACTTCTACCTGCCCTCAAGGGTGTGTATATTGTATAGGGGCAACTGTATGAAAAATTGGGGAGGAGGGGGCCGGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAG
Ensembl | human accession no.
NCBI accession no.
shipped in
ambient
storage temp.
−20°C
Quality Level
General description
MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
Legal Information
MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Jianwen Long et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 102, 1195-1202 (2018-05-02)
Melanoma has been a severe threat to human health, microRNAs play vital roles in the oncogenesis and progression of cancers. In this report, the roles and mechanism of miR-338-5p were investigated in the development of melanoma. A total of 46
Qing-Hui Zhang et al.
Digestive diseases and sciences, 60(7), 1967-1976 (2015-02-06)
This study was to investigate the effects and mechanisms of miR-362-3p on regulation of gastric cancer (GC) cell metastasis potential. We detected miR-362-3p level in GC and adjacent normal tissues and investigated the relationship with clinicopathological factors. Next, we analyzed
Muskan Floren et al.
Oncogene, 39(19), 3910-3925 (2020-03-24)
A principal challenge in treating acute myeloid leukemia (AML) is chemotherapy refractory disease. As such, there remains a critical need to identify key regulators of chemotherapy resistance in AML. In this study, we demonstrate that the membrane scaffold, CD82, contributes
Chao Huang et al.
Journal of extracellular vesicles, 9(1), 1692417-1692417 (2019-12-07)
Tumour metastasis suppressor KAI1/CD82 inhibits tumour cell movement. As a transmembrane protein, tetraspanin CD82 bridges the interactions between membrane microdomains of lipid rafts and tetraspanin-enriched microdomains (TEMs). In this study, we found that CD82 and other tetraspanins contain cholesterol recognition/interaction
Thomas B Layton et al.
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Fibrotic disorders are some of the most devastating and poorly treated conditions in developed nations, yet effective therapeutics are not identified for many of them. A major barrier for the identification of targets and successful clinical translation is a limited
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