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Merck
CN

EHU066021

Sigma-Aldrich

MISSION® esiRNA

targeting human PICK1

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关于此项目

UNSPSC代码:
41105324
NACRES:
NA.51

主要文件

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描述

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质量水平

100

产品线

MISSION®

表单

lyophilized powder

esiRNA cDNA靶序列

TCCCTGGACATTGTGTTGAAGAAAGTCAAGCACCGGCTGGTGGAGAACATGAGTTCAGGGACCGCAGATGCTCTGGGCCTGAGCCGGGCCATCCTGTGCAATGATGGGCTTGTCAAGAGGCTAGAGGAGCTGGAGCGGACCGCTGAGCTATACAAAGGGATGACGGAACACACCAAGAACCTCCTACGGGCCTTTTATGAGCTGTCGCAGACTCACCGGGCCTTTGGGGACGTGTTCTCCGTGATCGGGGTGCGGGAGCCCCAGCCAGCTGCGAGCGAGGCTTTTGTGAAGTTCGCCGATGCCCACCGCAGCATCGAGAAGTTCGGCATTCGGCTTCTGAAAACCATCAAGCCGATGCTGACGGATCTGAACACGTACCTCAACAAAGCCATCCCGGACACTCGCCTCACCATCAAGAAGTACCTGGACGTGAAGTTTGAGTACCTGTCGTACTGCCTGAAGGTG

基因组数据库 |人类登记号

ENSG00000100151

NCBI登记号

NM_001039583

运输

ambient

储存温度

−20°C

基因信息

human ... PICK1(9463), PICK1(9463)

一般描述

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

法律信息

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

10 - Combustible liquids

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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分析证书(COA)

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Xuan Ling Hilary Yong et al.
Cell reports, 33(4), 108312-108312 (2020-10-29)
Efficient retrieval of synaptic vesicles (SVs) is crucial to sustain synaptic transmission. Protein interacting with C-kinase 1 (PICK1) is a unique PDZ (postsynaptic density-95/disc-large/zona-occluden-1)- and BAR (Bin-Amphiphysin-Rvs )-domain-containing protein that regulates the trafficking of postsynaptic glutamate receptors. It is also
Haiyan Qiu et al.
Biochemical and biophysical research communications, 522(1), 14-20 (2019-11-19)
Diabetes mellitus is a metabolic disease characterized by an increase in blood glucose levels due to lack of insulin secretion. Previous studies have confirmed that PICK1 is critical for both β-cell function and glucose homeostasis. The aim of this study

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