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Merck
CN

EHU066021

MISSION® esiRNA

targeting human PICK1

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NACRES:
NA.51
UNSPSC Code:
41105324

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description

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product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

TCCCTGGACATTGTGTTGAAGAAAGTCAAGCACCGGCTGGTGGAGAACATGAGTTCAGGGACCGCAGATGCTCTGGGCCTGAGCCGGGCCATCCTGTGCAATGATGGGCTTGTCAAGAGGCTAGAGGAGCTGGAGCGGACCGCTGAGCTATACAAAGGGATGACGGAACACACCAAGAACCTCCTACGGGCCTTTTATGAGCTGTCGCAGACTCACCGGGCCTTTGGGGACGTGTTCTCCGTGATCGGGGTGCGGGAGCCCCAGCCAGCTGCGAGCGAGGCTTTTGTGAAGTTCGCCGATGCCCACCGCAGCATCGAGAAGTTCGGCATTCGGCTTCTGAAAACCATCAAGCCGATGCTGACGGATCTGAACACGTACCTCAACAAAGCCATCCCGGACACTCGCCTCACCATCAAGAAGTACCTGGACGTGAAGTTTGAGTACCTGTCGTACTGCCTGAAGGTG

Ensembl | human accession no.

ENSG00000100151

NCBI accession no.

NM_001039583

shipped in

ambient

storage temp.

−20°C

Quality Level

100

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

存储类别

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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Haiyan Qiu et al.
Biochemical and biophysical research communications, 522(1), 14-20 (2019-11-19)
Diabetes mellitus is a metabolic disease characterized by an increase in blood glucose levels due to lack of insulin secretion. Previous studies have confirmed that PICK1 is critical for both β-cell function and glucose homeostasis. The aim of this study
Xuan Ling Hilary Yong et al.
Cell reports, 33(4), 108312-108312 (2020-10-29)
Efficient retrieval of synaptic vesicles (SVs) is crucial to sustain synaptic transmission. Protein interacting with C-kinase 1 (PICK1) is a unique PDZ (postsynaptic density-95/disc-large/zona-occluden-1)- and BAR (Bin-Amphiphysin-Rvs )-domain-containing protein that regulates the trafficking of postsynaptic glutamate receptors. It is also

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