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Merck
CN

EHU080011

MISSION® esiRNA

targeting human ATE1

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NACRES:
NA.51
UNSPSC Code:
41105324

主要文件

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产品名称

MISSION® esiRNA, targeting human ATE1

description

Powered by Eupheria Biotech

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

TTGTGGCTATGGCTCCTTTCACCAGCAGTACTGGCTTGACGGAAAGATCATTGCTGTGGGGGTGATTGACATCCTCCCAAACTGTGTATCATCTGTGTATTTGTACTACGATCCTGATTATTCGTTTTTGTCTTTGGGCGTCTACTCTGCACTACGAGAAATTGCTTTTACTAGGCAGCTTCATGAGAAAACTTCTCAACTCAGCTATTATTATATGGGTTTCTACATTCATTCATGTCCCAAGATGAAATATAAGGGTCAGTATAGACCTTCTGATTTGCTGTGCCCTGAGACATATGTTTGGGTACCCATTGAGCAATGCCTGCCTTCACTTGAAAACTCCAAGTACTGCCGTTTCAACCAGGACCCAGAAGCAGTGGATGAGGATCGCAGTACGGAACCTGACCGATTGCAGGTGTTTCACAAGAGAGCCATCATGC

Ensembl | human accession no.

ENSG00000107669

NCBI accession no.

NM_001001976

shipped in

ambient

storage temp.

−20°C

Quality Level

100

Gene Information

human ... ATE1(11101), ATE1(11101)

相关类别

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

存储类别

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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Kanika Singh et al.
Scientific reports, 10(1), 598-598 (2020-01-19)
Myocardial hypertrophy, an inflammatory condition of cardiac muscles is a maladaptive response of the heart to biomechanical stress, hemodynamic or neurohormonal stimuli. Previous studies indicated that knockout of Arginyltransferase (ATE1) gene in mice and embryos leads to contractile dysfunction, defective
Chang Hoon Ji et al.
Molecular cell, 75(5), 1058-1072 (2019-08-04)
The endoplasmic reticulum (ER) is susceptible to wear-and-tear and proteotoxic stress, necessitating its turnover. Here, we show that the N-degron pathway mediates ER-phagy. This autophagic degradation initiates when the transmembrane E3 ligase TRIM13 (also known as RFP2) is ubiquitinated via

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