产品名称
MISSION® esiRNA, targeting human BMPR2
description
Powered by Eupheria Biotech
product line
MISSION®
form
lyophilized powder
esiRNA cDNA target sequence
TTTCACTGGATGGTAATGTAACCTTAAAAGCATCATAATAGGTAAAGTCTAATATTAGTTCCCTTAACAAAATCCTAACTGTATACCAGAATTAGGTCACTGAAAGAACTTGATTTGAATTACGTTTAGACAAAAATGATTTAATTGTAAATTCTTAAAACTTTCTAAATGCATAATTGGCAAAAAAAAAAACCCACTGTTACCAGTGTAGGAAGTTACAAGAAGGCACATACTGAATGCTGAAGTATACATATGCTATTTCTCTTAAACCTCAGAGCAACCATATGAGCATTGTAATTAATATTCCCATTTTACAGATGAGGAAACTGAAGCTAAGAGAAGCTAAGTAATATGCCCAAGGTCCACATCTAGTAACAGACAAAGCTGGGATTTCAGTCTATGTCTGCCTCTCTCCACATCTCTTTCATCCATACCACACTGCCTACATGCC
Ensembl | human accession no.
NCBI accession no.
shipped in
ambient
storage temp.
−20°C
Quality Level
Gene Information
human ... BMPR2(659), BMPR2(659)
General description
MISSION esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
Legal Information
MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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Wenhua Shi et al.
Journal of cellular physiology, 236(6), 4694-4708 (2020-12-08)
The aims of the present study were to examine the molecular mechanisms underlying sphingosine-1-phosphate (S1P)-induced rat pulmonary artery smooth muscle cells (PASMCs) proliferation/migration and to determine the effect of yes-associated protein (YAP) activation on S1P-induced PASMCs proliferation/migration and its potential
Tomohiko Fukuda et al.
Cell death discovery, 6(1), 139-139 (2020-12-11)
BMP signaling has been found to have tumor-promoting as well as tumor-suppressing effects in different types of tumors. In this study, we investigated the effects of BMP signaling and of BMP inhibitors on ovarian cancer (OC) cells in vitro and
Zhixian Yu et al.
PloS one, 11(12), e0168334-e0168334 (2016-12-16)
Approximately 30% of tumor endothelial cells have over-duplicated (>2) centrosomes, which may contribute to abnormal vessel function and drug resistance. Elevated levels of vascular endothelial growth factor A induce excess centrosomes in endothelial cells, but how other features of the
Alex Yuri Simões Sato et al.
Atherosclerosis, 235(1), 45-55 (2014-05-13)
Monocytes and macrophages, together with vascular smooth muscle cells (VSMCs), play key roles at all stages of atherogenesis. There is also growing evidence that BMP signaling is involved in vascular diseases, including atherosclerosis. Here we evaluate the role played by
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