产品名称
MISSION® esiRNA, targeting human PEMT
description
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product line
MISSION®
form
lyophilized powder
esiRNA cDNA target sequence
CTCGTGCTCTCCAGCTTCTTTGCACTGGGGTTCGCTGGAACTTTCCTAGGTGATTACTTCGGGATCCTCAAGGAGGCGAGAGTGACCGTGTTCCCCTTCAACATCCTGGACAACCCCATGTACTGGGGAAGCACAGCCAACTACCTGGGCTGGGCCATCATGCACGCCAGCCCCACGGGCCTGCTCCTGACGGTGCTGGTGGCCCTCACCTACATAGTGGCTCTCCTATACGAAGAGCCCTTCACCGCTGAGATCTACCGGCAGAAAGCCTCCGGGTCCCACAAGAGGAGCTGATTGAGCTGCAACAGCTTTGCTGAAGGCCTGGCCAGCCTCCTGGCCTGCCCCAAGTGGCAGGCCCTGCGCAGGGCGAGAATGGTGCCTGCTGCTCAGGGCTCGCCCCCGGCGTGGGCTGCCCCAGTGCCTTGGAACCTGCTGCCTTGGGGACCCTGGACGTGCCGACATATGGCCATTGAGCTCCAACCCACACATTCCCATTC
Ensembl | human accession no.
NCBI accession no.
shipped in
ambient
storage temp.
−20°C
Quality Level
Gene Information
human ... PEMT(10400), PEMT(10400)
General description
MISSION esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
Legal Information
MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Natalia Presa et al.
Biochimica et biophysica acta. Molecular basis of disease, 1866(10), 165853-165853 (2020-06-06)
Phosphatidylethanolamine N-methyltransferase (PEMT) is a small integral membrane protein that converts phosphatidylethanolamine (PE) into phosphatidylcholine (PC). It has been previously reported that, unexpectedly, PEMT deficiency protected from high-fat diet (HFD)-induced obesity and insulin resistance, pointing to a possible role of
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