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Merck
CN

EHU147251

Sigma-Aldrich

MISSION® esiRNA

targeting human EIF5A2

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关于此项目

UNSPSC代码:
41105324
NACRES:
NA.51

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描述

Powered by Eupheria Biotech

质量水平

100

产品线

MISSION®

表单

lyophilized powder

esiRNA cDNA靶序列

ATGGTCATGCCAAGGTTCACCTTGTTGGAATTGATATTTTCACGGGCAAAAAATATGAAGATATTTGTCCTTCTACTCACAACATGGATGTTCCAAATATTAAGAGAAATGATTATCAACTGATATGCATTCAAGATGGTTACCTTTCCCTGCTGACAGAAACTGGTGAAGTTCGTGAGGATCTTAAACTGCCAGAAGGTGAACTAGGCAAAGAAATAGAGGGAAAATACAATGCAGGTGAAGATGTACAGGTGTCTGTCATGTGTGCAATGAGTGAAGAATATGCTGTAGCCATAAAACCCTGCAAATAAACGGAAACATCAGGCATGAACACTGTTTATGTCTGAATCAACTGCAGATCTAATTTGGTTCTAAGTTGTCACCAAAGCTATAGCCTTCATAAGCAACCTCATTTCTTTTTTTAATTGTTTTCAGATTGTGCTGGGTTAGTTTTGCA

基因组数据库 |人类登记号

ENSG00000163577

NCBI登记号

NM_020390

运输

ambient

储存温度

−20°C

基因信息

human ... EIF5A2(56648), EIF5A2(56648)

一般描述

MISSION esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

法律信息

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

10 - Combustible liquids

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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Ying Bao et al.
International journal of biological sciences, 16(5), 827-837 (2020-02-20)
We investigated the role of microRNA (miR)-9 in modulating chemoresistance in hepatocellular carcinoma (HCC) cells. MiR-9 was overexpressed or knocked down in HCC cell lines. Cell viability, cell proliferation, the expression of EIF5A2 and the epithelial-mesenchymal transition (EMT)-related proteins were
Xiulong Zhong et al.
Bioengineered, 11(1), 619-627 (2020-06-12)
Overexpression of eukaryotic initiation factor- 5A2 (eIF5A2) has been implicated in promoting tumor cell migration and invasion in many cancers. However, whether eIF5A2 could be as the target for prostate cancer (PCa) treatment is still unknown. In this study, small
Yu Liu et al.
Breast cancer (Tokyo, Japan), 22(6), 602-607 (2014-03-19)
The eIF5A2 gene (encoding the eukaryotic initiation factor 5A2) located at 3q26 is a putative oncogene that is overexpressed in colon and rectal carcinomas, lung cancer and hepatocellular carcinoma. EIF5A2 overexpression correlates significantly with tumor metastasis and is an adverse

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