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Merck
CN

EHU154501

MISSION® esiRNA

targeting human SH2D2A

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NACRES:
NA.51
UNSPSC Code:
41105324

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description

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product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

CCTGTCCTACGGAAGAGCTGGTCCAGGCCTGTCCCAGGAGGCCAGAATACAGGTGGCTCCCAGCTGCATTCTGAGAACTCTGTGATTGGGCAAGGCCCTCCCCTGCCCCACCAGCCCCCACCCGCCTGGAGACACACCCTCCCCCACAATCTTTCTAGACAGGTGCTTCAGGACAGAGGACAGGCATGGCTTCCCCTTGGGCCTCCTCAGTAGGCGGTCTGGCCTGACCCCCAACAAAGAAGCCTGGAGGTCAGAGAAGCAAATGCGGAGCCTGCTCCCTCCTAAGAAGATCCCAAGAATCCAATGGCTCAGTCCTTGGTGATCTAAGACAGCAAAGAAGTGTGCAAGGAGGGCCCTGTTAGCTCCCACTGTCCTGGTTTCTCCTCCTGGAGTCTAATTTCCTTGGCCCTCTGAGCCTTTTGAGTCTGGG

Ensembl | human accession no.

ENSG00000027869

NCBI accession no.

NM_003975

shipped in

ambient

storage temp.

−20°C

Quality Level

100

General description

MISSION esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

存储类别

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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Zuyue Sun et al.
The Journal of experimental medicine, 209(7), 1363-1377 (2012-06-13)
Regulation of vascular endothelial (VE) growth factor (VEGF)-induced permeability is critical in physiological and pathological processes. We show that tyrosine phosphorylation of VEGF receptor 2 (VEGFR2) at Y951 facilitates binding of VEGFR2 to the Rous sarcoma (Src) homology 2-domain of
Amar Singh et al.
Nature communications, 10(1), 3495-3495 (2019-08-04)
Immune tolerance to allografts has been pursued for decades as an important goal in transplantation. Administration of apoptotic donor splenocytes effectively induces antigen-specific tolerance to allografts in murine studies. Here we show that two peritransplant infusions of apoptotic donor leukocytes

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