产品名称
MISSION® esiRNA, targeting human HPS1
description
Powered by Eupheria Biotech
product line
MISSION®
form
lyophilized powder
esiRNA cDNA target sequence
AGGACACCCTCCAAACACTGGTTCCCCACTGCCCTGTGCCTTCCGGCCCCAGAAGGATCTTCCTGGATGCCAACGTGAAGGAAAGCTACTGCCCCCTAGTGCCCCACACCATGTACTGCCTGCCCCTGTGGCAGGGCATCAACCTGGTGCTCCTGACCAGGAGCCCCAGCGCGCCCCTGGCCCTGGTTCTGTCCCAGCTGATGGATGGCTTCTCCAT
Ensembl | human accession no.
NCBI accession no.
shipped in
ambient
storage temp.
−20°C
Quality Level
Gene Information
human ... HPS1(3257), HPS1(3257)
General description
MISSION esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
Legal Information
MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Saket Ahuja et al.
American journal of physiology. Lung cellular and molecular physiology, 310(6), L519-L531 (2016-01-01)
Hermansky-Pudlak syndrome (HPS) is a rare autosomal recessive disorder, and some patients with HPS develop pulmonary fibrosis, known as HPS-associated interstitial pneumonia (HPSIP). We have previously reported that HPSIP is associated with severe surfactant accumulation, lysosomal stress, and alveolar epithelial
Govindasamy-Muralidharan Karthik et al.
Cancer letters, 367(1), 76-87 (2015-07-26)
Breast cancer cells with stem cell characteristics (CSC) are a distinct cell population with phenotypic similarities to mammary stem cells. CSCs are important drivers of tumorigenesis and the metastatic process. Tamoxifen is the most widely used hormonal therapy for estrogen
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